Evidence map›Paper›PMID 36624273›Full record

ReviewNature reviews. Nephrology2023

Regulation of FGF23 production and phosphate metabolism by bone-kidney interactions.

Rafiou Agoro, Kenneth E White

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  15. Lower calcium/phosphorus ratio is associated with the severity of deformity in patients with scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  16. New knock-in mouse linesJBMR plus · 2026
    Article
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rafiou AgoroDepartment of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.ORCID 0000-0002-5461-7685
Kenneth E WhiteDepartment of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. kenewhit@iu.edu.
Indiana University School of Medicine

Funding

Changes in phosphate metabolism cause pathologic cardiac remodeling in chronic kidney disease (CKD)R01HL145528 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI FAUL, CHRISTIAN, WHITE, KENNETH E · 2019 to 2022
$2.4M
Novel Control of FGF23 in Metabolic Bone DiseaseR01DK112958 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI WHITE, KENNETH E · 2018 to 2020
$698k
Conditional Isolation of Fgf23 ActivityR21AR059278 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI WHITE, KENNETH E · 2010 to 2011
$373k
Controlling renal oxidative stress in CKD via targeting FGF23 bioactivityK99DK129705 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI AGORO, RAFIOU · 2022 to 2023
$178k
NHLBI NIH HHS R01 HL145528NIAMS NIH HHS R21 AR059278NIDDK NIH HHS K99 DK129705NIDDK NIH HHS R01 DK112958
6 · The paper itself

Abstract

The bone-derived hormone fibroblast growth factor 23 (FGF23) functions in concert with parathyroid hormone (PTH) and the active vitamin D metabolite, 1,25(OH)

Indexed as

Bone and BonesFibroblast Growth Factor-23KidneyFibroblast Growth FactorsHumansKlotho ProteinsPhosphatesVitamin DFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsKlotho ProteinsPhosphatesVitamin D

Identifiers

PMID36624273
OpenAlexW4313837144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.