Evidence map›Paper›PMID 36624191›Full record

ArticleJournal of cancer research and clinical oncology2023

Working situation and burden of work limitations in sarcoma patients: results from the multi-center prospective PROSa study.

Sergio Armando Zapata Bonilla, Marius Fried, Susanne Singer, Leopold Hentschel, Stephan Richter, Peter Hohenberger, Bernd Kasper, Dimosthenis Andreou, Daniel Pink, Karin Arndt and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Sergio Armando Zapata BonillaClinic and Polyclinic for Internal Medicine III, Haematology and Medical Oncology/University Centre for Tumor Diseases (UCT), University Hospital Johannes Gutenberg, University Hospital Mainz, Mainz, Germany. sergio.zapatabonilla@unimedizin-mainz.de.
Marius FriedClinic and Polyclinic for Internal Medicine III, Haematology and Medical Oncology/University Centre for Tumor Diseases (UCT), University Hospital Johannes Gutenberg, University Hospital Mainz, Mainz, Germany.
Susanne SingerInstitute for Medical Biostatistics, Epidemiology and Informatics, University Hospital Mainz, Mainz, Germany.
Leopold HentschelNational Center for Tumor Diseases Dresden (NCT/UCC), Dresden, Germany.
Stephan RichterClinic and Polyclinic for Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
Peter HohenbergerDivision of Surgical Oncology & Thoracic Surgery, Mannheim University Medical Center, University of Heidelberg, Heidelberg, Germany.
Bernd KasperSarcoma Unit, Mannheim Cancer Center (MCC), Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany.
Dimosthenis AndreouDepartment of General Orthopedics and Tumor Orthopedics, University Hospital Munster, Munster, Germany.
Daniel PinkSarcoma Center Berlin-Brandenburg, Helios Hospital Bad Saarow, Brandenburg, Germany.
Karin ArndtGerman Sarcoma Foundation, Woelfersheim, Germany.
Martin BornhäuserNational Center for Tumor Diseases Dresden (NCT/UCC), Dresden, Germany.
Jochen SchmittNational Center for Tumor Diseases Dresden (NCT/UCC), Dresden, Germany.
Markus K SchulerClinic and Polyclinic for Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
Martin EichlerNational Center for Tumor Diseases Dresden (NCT/UCC), Dresden, Germany.
Heidelberg University · DEJohannes Gutenberg University Mainz · DEUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Heidelberg · DEGerman Cancer Research Center · DEUniversitätsmedizin Greifswald · DEUniversity Hospital Münster · DE

Funding

Deutsche Krebshilfe 111713
6 · The paper itself

Abstract

purposeWe investigated predictors of limitations in work performance, odds of drop out of work, and odds of receiving disability pension in sarcoma patients.

methodsWe measured clinical and sociodemographic data in adult sarcoma patients and recorded if the patients received a (1) disability pension at baseline or (2) had dropped out of work 1 year after initial assessment. (3) Work limitations were assessed using the Work-limitations questionnaire (WLQ

results(1) Amongst 364 analyzed patients, odds to receive a disability pension were higher in patients with abdominal tumors, older patients, high grade patients and with increasing time since diagnosis. (2) Of 356 patients employed at baseline, 21% (n = 76) had dropped out of work after 1 year. The odds of dropping out of work were higher in bone sarcoma patients and in patients who received additive radiotherapy ± systemic therapy compared with patients who received surgery alone. Odds of dropping out of work were less amongst self-employed patients and dropped with increasing time since diagnosis. (3) Work limitations were higher in woman and increased with age. Patients with bone and fibrous sarcomas were more affected than liposarcoma patients. Patients with abdominal tumors reported highest restrictions. Sarcoma treatment in the last 6 months increased work limitations.

conclusionWork limitations, drop out of work and dependence on a disability pension occurs frequently in patients with sarcoma adding to the burden of this condition. We were able to identify vulnerable groups in both the socioeconomic and disease categories.

Indexed as

Persons with DisabilitiesSarcomaAdultFemaleHumansPensionsProspective StudiesDisability pensionDrop out of workLimitations at workRare diseasesReturn to workSarcomaWorking situationWork-limitations questionnaire

Identifiers

PMID36624191
PMCPMC10356622
OpenAlexW4313880430

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.