Evidence map›Paper›PMID 36624011›Full record

ArticleVaccine2023

COVID-19 vaccination refusal trends in Kenya over 2021.

Ryan T Rego, Brooke Kenney, Anthony K Ngugi, Leon Espira, James Orwa, Geoffrey H Siwo, Christabel Sefa, Jasmit Shah, Eileen Weinheimer-Haus, Antonia Johanna Sophie Delius and 9 more

Abstract read
In one paragraph

Article in Vaccine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Kenyans' Perceptions of the Risks of COVID-19 Vaccines: A Scoping Review.Pan-African journal of health and environmental science · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ryan T RegoCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA. Electronic address: RegoR@UMich.edu.
Brooke KenneyCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Anthony K NgugiDepartment of Population Health, Aga Khan University, Nairobi, Kenya.
Leon EspiraCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA.
James OrwaDepartment of Population Health, Aga Khan University, Nairobi, Kenya.
Geoffrey H SiwoCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Christabel SefaCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA.
Jasmit ShahDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya; Brain and Mind Institute, Aga Khan University, Nairobi, Kenya.
Eileen Weinheimer-HausCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Antonia Johanna Sophie DeliusWorld Bank Group, Washington, DC, USA.
Utz Johann PapeWorld Bank Group, Washington, DC, USA; University of Goettingen, Goettingen, Germany.
Furqan B IrfanInstitute of Global Health, Michigan State University, Lansing, MI, USA.
Amina AbubakarInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Reena ShahDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya.
Abram WagnerSchool of Public Health, University of Michigan, Ann Arbor, MI, USA.
Joseph KolarsCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Matthew L BoultonSchool of Public Health, University of Michigan, Ann Arbor, MI, USA.
Timothy HoferCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Akbar K WaljeeCenter for Global Health Equity, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA; Michigan Integrated Center for Health Analytics and Medical Prediction (MiCHAMP), Ann Arbor, MI, USA.

Funding

UZIMA-DS: UtiliZing health Information for Meaningful Impact in East Africa through Data ScienceU54TW012089 · FIC · AGA KHAN UNIVERSITY (KENYA) · PI Amina Abubakar Ali, Akbar K Waljee · 2021 to 2026
$7.7M
FIC NIH HHS U54 TW012089
6 · The paper itself

Abstract

backgroundVaccination refusal exacerbates global COVID-19 vaccination inequities. No studies in East Africa have examined temporal trends in vaccination refusal, precluding addressing refusal. We assessed vaccine refusal over time in Kenya, and characterized factors associated with changes in vaccination refusal.

methodsWe analyzed data from the Kenya Rapid Response Phone Survey (RRPS), a household cohort survey representative of the Kenyan population including refugees. Vaccination refusal (defined as the respondent stating they would not receive the vaccine if offered to them at no cost) was measured in February and October 2021. Proportions of vaccination refusal were plotted over time. We analyzed factors in vaccination refusal using a weighted multivariable logistic regression including interactions for time.

findingsAmong 11,569 households, vaccination refusal in Kenya decreased from 24 % in February 2021 to 9 % in October 2021. Vaccination refusal was associated with having education beyond the primary level (-4.1[-0.7,-8.9] percentage point difference (ppd)); living with somebody who had symptoms of COVID-19 in the past 14 days (-13.72[-8.9,-18.6]ppd); having symptoms of COVID-19 in the past 14 days (11.0[5.1,16.9]ppd); and distrusting the government in responding to COVID-19 (14.7[7.1,22.4]ppd). There were significant interactions with time and: refugee status and geography, living with somebody with symptoms of COVID-19, having symptoms of COVID-19, and believing in misinformation.

interpretationThe temporal reduction in vaccination refusal in Kenya likely represents substantial strides by the Kenyan vaccination program and possible learnt lessons which require examination. Going forward, there are still several groups which need specific targeting to decrease vaccination refusal and improve vaccination equity, including those with lower levels of education, those with recent COVID-19 symptoms, those who do not practice personal COVID-19 mitigation measures, refugees in urban settings, and those who do not trust the government. Policy and program should focus on decreasing vaccination refusal in these populations, and research focus on understanding barriers and motivators for vaccination.

Indexed as

COVID-19COVID-19 VaccinesAfrica, EasternHumansKenyaVaccinationVaccination RefusalCOVID-19 VaccinesCOVID-19HesitancyKenyaRefugeeRefusalVaccination

Identifiers

PMID36624011
PMCPMC9808414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.