Evidence map›Paper›PMID 36623963›Full record

ArticleAmerican journal of surgery2023

The role of ECMO in COVID-19 acute respiratory failure: Defining risk factors for mortality.

Jared Gallaher, Lauren Raff, Andrew Schneider, Trista Reid, Melissa B Miller, Olivia Boddie, Anthony Charles

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jared GallaherUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA. Electronic address: jared_gallaher@med.unc.edu.
Lauren RaffUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA.
Andrew SchneiderUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA.
Trista ReidUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA.
Melissa B MillerUniversity of North Carolina at Chapel Hill School of Medicine, Department of Pathology and Laboratory Medicine, Chapel Hill, NC, USA.
Olivia BoddieUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA.
Anthony CharlesUniversity of North Carolina at Chapel Hill School of Medicine, Department of Surgery, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVeno-venous extracorporeal membrane oxygenation (VV ECMO) utilization increased substantially during the COVID-19 pandemic, but without patient selection criteria.

methodsWe conducted a retrospective review of all adult patients with COVID-19-associated ARDS placed on VV ECMO at our institution from April 2020 through June 2022.

results162 patients were included (n = 95 Pre-Delta; n = 58 Delta; n = 9 Omicron). The frequency of ECMO duration greater than three weeks was variable by pandemic period (17% pre-Delta, 41% Delta, 22% Omicron, p = 0.003). In-hospital mortality was 60.5%. Age ≥50 years (RR 1.28, 95% CI 1.01, 1.62), ≥7 days of respiratory support (1.39, 95% CI 1.05, 1.83) and pre-cannulation renal failure requiring dialysis (RR 1.42, 95% CI 1.13, 1.78) were associated with mortality.

conclusionsIn this cohort of VV ECMO patients with COVID-19, older age, a longer duration of pre-ECMO respiratory support, and pre-ECMO renal failure all increased the risk of mortality by approximately 30%.

Indexed as

COVID-19Extracorporeal Membrane OxygenationRenal InsufficiencyRespiratory Distress SyndromeRespiratory InsufficiencyAdultHumansMiddle AgedPandemicsRetrospective StudiesRisk FactorsARDSCOVID-19VV ECMO

Identifiers

PMID36623963
PMCPMC9788991
OpenAlexW4313530816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.