Evidence map›Paper›PMID 36623877›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Spontaneous Activity of the Local GABAergic Synaptic Network Causes Irregular Neuronal Firing in the External Globus Pallidus.

James A Jones, Matthew H Higgs, Erick Olivares, Jacob Peña, Charles J Wilson

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Propagation of Oscillations in the Indirect Pathway of the Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

James A JonesDepartment of Neuroscience, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, Texas 78249.
Matthew H HiggsAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104.
Erick OlivaresDepartment of Neuroscience, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, Texas 78249.ORCID 0000-0003-2069-5789
Jacob PeñaDepartment of Neuroscience, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, Texas 78249.
Charles J WilsonDepartment of Neuroscience, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, Texas 78249.
The University of Texas at San Antonio · USOklahoma Medical Research Foundation · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
Oscillations and Resonance in Basal Ganglia CircuitsR35NS097185 · NINDS · UNIVERSITY OF TEXAS SAN ANTONIO · PI WILSON, CHARLES J · 2017 to 2024
$5.3M
MARC at the University of Texas at San AntonioT34GM145507 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J, CASSILL, AARON · 2022 to 2024
$1.5M
Neuron heterogeneity and network dynamic control of synaptic responses in the external globus pallidusF31NS127499 · NINDS · UNIVERSITY OF TEXAS SAN ANTONIO · PI JONES, JAMES · 2022 to 2023
$56k
NIGMS NIH HHS R25 GM060655NIGMS NIH HHS T34 GM145507NINDS NIH HHS F31 NS127499NINDS NIH HHS R35 NS097185
6 · The paper itself

Abstract

Autonomously firing GABAergic neurons in the external globus pallidus (GPe) form a local synaptic network. In slices, most GPe neurons receive a continuous inhibitory synaptic barrage from 1 or 2 presynaptic GPe neurons. We measured the barrage's effect on the firing rate and regularity of GPe neurons in male and female mice using perforated patch recordings. Silencing the firing of parvalbumin-positive (PV

Indexed as

GABAergic NeuronsGlobus PallidusAnimalsAxonsBasic Helix-Loop-Helix ProteinsFemaleMaleMiceNerve Tissue ProteinsParvalbuminsBasic Helix-Loop-Helix ProteinsNerve Tissue ProteinsNpas1 protein, mouseParvalbuminsautonomous firingbasal gangliacollateral networkglobus pallidusoscillationsrecurrent inhibition

Identifiers

PMID36623877
PMCPMC9987574
OpenAlexW4313837195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.