Evidence map›Paper›PMID 36623197›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The MAPK-Alfin-like 7 module negatively regulates ROS scavenging genes to promote NLR-mediated immunity.

Dingliang Zhang, Zongyu Gao, He Zhang, Yizhou Yang, Xinxin Yang, Xiaofei Zhao, Hailong Guo, Ugrappa Nagalakshmi, Dawei Li, Savithramma P Dinesh-Kumar and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
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  11. From perception to action: MAPKs in plant-virus interactions.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  12. Article
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  17. Review
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  19. Crop antiviral defense: Past and future perspective.Science China. Life sciences · 2024
    Review
  20. Identification ofPlants (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Dingliang ZhangState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-2740-3585
Zongyu GaoState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
He ZhangState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
Yizhou YangState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-6886-6797
Xinxin YangState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-5086-5553
Xiaofei ZhaoState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
Hailong GuoState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Ugrappa NagalakshmiDepartment of Plant Biology and the Genome Center, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0001-7981-5031
Dawei LiState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-4133-1263
Savithramma P Dinesh-KumarDepartment of Plant Biology and the Genome Center, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0001-5738-316X
Yongliang ZhangState Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-6790-1044
China Agricultural University · CNUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleotide-binding leucine-rich repeat (NLR) receptor-mediated immunity includes rapid production of reactive oxygen species (ROS) and transcriptional reprogramming, which is controlled by transcription factors (TFs). Although some TFs have been reported to participate in NLR-mediated immune response, most TFs are transcriptional activators, and whether and how transcriptional repressors regulate NLR-mediated plant defenses remains largely unknown. Here, we show that the Alfin-like 7 (AL7) interacts with N NLR and functions as a transcriptional repressor. Knockdown and knockout of

Indexed as

Plant ProteinsTranscription FactorsLeucineNicotianaNucleotidesPlant ImmunityProtein DomainsReactive Oxygen SpeciesLeucineNucleotidesPlant ProteinsReactive Oxygen SpeciesTranscription FactorsAlfin-like 7MAPKsN NLR immune receptorTMVtranscriptional repressor

Identifiers

PMID36623197
PMCPMC9934166
OpenAlexW4313856028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.