ArticleMagnetic resonance in medicine2023
Quantification of blood-brain barrier water exchange and permeability with multidelay diffusion-weighted pseudo-continuous arterial spin labeling.
Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Relationship between brain iron dynamics and blood-brain barrier function during childhood: a quantitative magnetic resonance imaging study.Fluids and barriers of the CNS · 2023Trial
- Simultaneous measurement of water transport across the blood-brain and blood-CSF barrier in the human brain with arterial spin labeling MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Accelerated MCDW-pCASL Using Subspace Low-Rank Reconstruction for Quantification of BBB Water Exchange and Permeability.medRxiv : the preprint server for health sciences · 2026Article
- Non-Contrast Assessment of Blood-Brain Barrier Permeability to Water: Improved Signal Modeling and Data Acquisition.Magnetic resonance in medicine · 2026Article
- Measuring blood-brain barrier dysfunction: a critical appraisal of fluid biomarkers, in vitro models, in vivo imaging, and post-mortem approaches.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Article
- On the structural and practical identifiability of multi-echo BBB-ASL tracer kinetic models.Magnetic resonance in medicine · 2026Article
- Repeatability of diffusion-weighted arterial spin labeling MRI for mapping blood-brain barrier water exchange rate at different postlabel delays.Magnetic resonance in medicine · 2026Article
- Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study.Fluids and barriers of the CNS · 2025Article
- Biomarkers of blood-brain barrier and neurovascular unit integrity in human cognitive impairment and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Research hotspots and frontiers of glymphatic system and Alzheimer's disease: a bibliometrics analysis.Frontiers in aging neuroscience · 2025Article
- Article
- Progress in magnetic resonance imaging of the glymphatic system.Magnetic resonance letters · 2024Review
- Water exchange across the blood-brain barrier and epilepsy: Review on pathophysiology and neuroimaging.Epilepsia open · 2024Review
- Arterial Spin Labeling: Key Concepts and Progress Towards Use as a Clinical Tool.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- Age-Related Decline in Blood-Brain Barrier Function is More Pronounced in Males than Females in Parietal and Temporal Regions.bioRxiv : the preprint server for biology · 2024Article
- Article
- Regional differences in the link between water exchange rate across the blood-brain barrier and cognitive performance in normal aging.GeroScience · 2024Article
- Quantification of TMagnetic resonance in medicine · 2023Article
- Contributions of blood-brain barrier imaging to neurovascular unit pathophysiology of Alzheimer's disease and related dementias.Frontiers in aging neuroscience · 2023Review
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5 authors.
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Abstract
purposeTo present a pulse sequence and mathematical models for quantification of blood-brain barrier water exchange and permeability.
methodsMotion-compensated diffusion-weighted (MCDW) gradient-and-spin echo (GRASE) pseudo-continuous arterial spin labeling (pCASL) sequence was proposed to acquire intravascular/extravascular perfusion signals from five postlabeling delays (PLDs, 1590-2790 ms). Experiments were performed on 11 healthy subjects at 3 T. A comprehensive set of perfusion and permeability parameters including cerebral blood flow (CBF), capillary transit time (τ
resultsUsing three-compartment SPA modeling, group-averaged CBF = 51.5/36.8 ml/100 g/min, k
conclusionMCDW-pCASL allows visualization of intravascular/extravascular ASL signals across multiple PLDs. The three-compartment SPA model provides a comprehensive measurement of blood-brain barrier water dynamics from group-averaged data, and a simplified LRL method was proposed for individual k
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