ArticleCirculation2023
Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct.
Abstract readLetter
In one paragraph
Article in Circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Dual-Target Cardiac Regeneration: ControllableCirculation · 2026Article
- Epigenetic Control of Mammalian Cardiomyocyte Proliferation.Current cardiology reports · 2026Review
- The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development.Cell death and differentiation · 2026Article
- Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation.Nature reviews. Cardiology · 2025Review
- Unraveling the Link Between Cardiomyocyte Endoreplication and Hypertrophy.Circulation research · 2025Article
- Targeting Cardiomyocyte PCNA and POLD1 Prevents Pathologic Myocardial Hypertrophy.Circulation research · 2025Article
- Intronic RNAscope probes enable precise identification of cardiomyocyte nuclei and cell cycle activity.Communications biology · 2025Article
- Dynamic map illuminates Hippo-cMyc module crosstalk driving cardiomyocyte proliferation.Development (Cambridge, England) · 2025Article
- The E2F family: a ray of dawn in cardiomyopathy.Molecular and cellular biochemistry · 2025Review
- Amplified centrosomes-more than just a threat.EMBO reports · 2024Review
Corrections and comments
- Commented on by
Authors and funding
12 authors.
Zhe Yu *Skaggs School of Pharmacy and Pharmaceutical Sciences (Z.Y., L.Z., S.M.E.), University of California at San Diego, La Jolla.
Lunfeng Zhang *Skaggs School of Pharmacy and Pharmaceutical Sciences (Z.Y., L.Z., S.M.E.), University of California at San Diego, La Jolla.
Paola CattaneoInstitute of Genetic and Biomedical Research (IRGB), UOS of Milan, National Research Council of Italy (P.C.).
Nuno Guimarães-CamboaInstitute of Cardiovascular Regeneration, Goethe University, Frankfurt, Germany (P.C., N.G.-C.).
Xi FangDepartment of Medicine (X.F., Y.G., K.L.P., J.B., J.C., S.M.E.), University of California at San Diego, La Jolla.ORCID 0000-0001-7816-8821
Yusu GuDepartment of Medicine (X.F., Y.G., K.L.P., J.B., J.C., S.M.E.), University of California at San Diego, La Jolla.
Kirk L PetersonDepartment of Medicine (X.F., Y.G., K.L.P., J.B., J.C., S.M.E.), University of California at San Diego, La Jolla.
Julius BogomolovasDepartment of Medicine (X.F., Y.G., K.L.P., J.B., J.C., S.M.E.), University of California at San Diego, La Jolla.
Cecilia CuitinoDepartment of Radiation Oncology, Arthur G. James Hospital/Ohio State Comprehensive Cancer Center, Columbus (C.C.).
Gustavo W LeoneMedical College of Wisconsin Cancer Center, Department of Biochemistry, Medical College of Wisconsin, Wauwatosa (G.W.L.).
Ju ChenDepartment of Medicine (X.F., Y.G., K.L.P., J.B., J.C., S.M.E.), University of California at San Diego, La Jolla.ORCID 0000-0001-7674-4776
Sylvia M EvansSkaggs School of Pharmacy and Pharmaceutical Sciences (Z.Y., L.Z., S.M.E.), University of California at San Diego, La Jolla.ORCID 0000-0001-5035-3697
Funding
Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1MU of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0MRenewing the heart: cardiomyocyte cell cycle regulationR35HL144984 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EVANS, SYLVIA M · 2019 to 2025
$6.1MNEDD4 in right ventricular developmentR01HL158761 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2021 to 2025
$2.5MProtein Kinase Novel 2 (PKN2) in heartR01HL155826 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, JU · 2021 to 2024
$2.2MNovel function of a mitochondria phosphatase in cardiac developmentR01HL157119 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, JU · 2021 to 2024
$2.2MNuclear envelope protein LEMD2 in heartR01HL158981 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, JU · 2021 to 2024
$2.2MMolecular mechanisms and treatment of cardiomyopathy in Barth SyndromeR01HL157115 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2021 to 2025
$2.0MPRDM16 in cardiac developmentR01HL153032 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, JU · 2020 to 2023
$1.6MMediator complex in cardiac development and functionR00HL143210 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2020 to 2022
$736kNHLBI NIH HHS R00 HL143210NHLBI NIH HHS R01 HL153032NHLBI NIH HHS R01 HL155826NHLBI NIH HHS R01 HL157115NHLBI NIH HHS R01 HL157119NHLBI NIH HHS R01 HL158761NHLBI NIH HHS R01 HL158981NHLBI NIH HHS R35 HL144984NHLBI NIH HHS T32 HL007444NINDS NIH HHS P30 NS047101
Abstract
PubMed holds no abstract for this paper.
Indexed as
DiploidyMyocytes, CardiacCell ProliferationE2F Transcription FactorsHumansInfarctionRegenerationE2F Transcription FactorsE2f7E2f8heart regenerationmononuclear diploid cardiomyocytespolyploidizationproliferation
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.