Evidence map›Paper›PMID 36622628›Full record

ArticleIrish journal of medical science2023

Outcomes of COVID-19 in people with rheumatic and musculoskeletal disease in Ireland over the first 2 years of the pandemic.

Richard Conway, Elena Nikiphorou, Christiana A Demetriou, Candice Low, Kelly Leamy, John G Ryan, Ronan Kavanagh, Alexander D Fraser, John J Carey, Paul O'Connell and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Long COVID in autoimmune rheumatic diseases.Rheumatology international · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 6 countries.

Richard ConwayDepartment of Rheumatology, St. James's Hospital, James Street, Dublin 8, Ireland. drrichardconway@gmail.com.ORCID http://orcid.org/0000-0003-2538-3362
Elena NikiphorouDepartment of Rheumatology, King's College Hospital, London, UK.
Christiana A DemetriouDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Candice LowDepartment of Rheumatology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Kelly LeamyDepartment of Rheumatology, Mater Misericordiae Hospital, Dublin 1, Ireland.
John G RyanDepartment of Rheumatology, Cork University Hospital, Wilton, Cork, Ireland.
Ronan KavanaghGalway Clinic, Galway, Ireland.
Alexander D FraserDepartment of Rheumatology, University Hospitals Limerick, Limerick, Ireland.
John J CareyDepartment of Rheumatology, Galway University Hospitals, Galway, Ireland.
Paul O'ConnellDepartment of Rheumatology, Beaumont Hospital, Dublin 9, Ireland.
Rachael M FloodTrinity College Dublin, Dublin, Ireland.
Ronan H MullanTrinity College Dublin, Dublin, Ireland.
David J KaneTrinity College Dublin, Dublin, Ireland.
Frances StaffordBlackrock Clinic, Dublin, Ireland.
Philip C RobinsonFaculty of Medicine, University of Queensland, Brisbane, Qld, Australia.
Jean W LiewSection of Rheumatology, Boston University School of Medicine, Boston, MA, USA.
Rebecca GraingerDepartment of Medicine, University of Otago, Wellington, New Zealand.
Geraldine M McCarthyDepartment of Rheumatology, Mater Misericordiae Hospital, Dublin 1, Ireland.
COVID-19 Global Rheumatology Alliance
Trinity College Dublin · IEMater Misericordiae University Hospital · IEBoston University · USCork University Hospital · IEGalway Clinic · IEKing's College London · GBOllscoil na Gaillimhe – University of Galway · IERoyal College of Surgeons in Ireland · IESt. Vincent's University Hospital · IEThe University of Queensland · AUUniversity of Limerick · IEUniversity of Nicosia · CYUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor COVID-19 outcomes occur with higher frequency in people with rheumatic and musculoskeletal diseases (RMD). Better understanding of the factors involved is crucial to informing patients and clinicians regarding risk mitigation.

aimTo describe COVID-19 outcomes for people with RMD in Ireland over the first 2 years of the pandemic.

methodsData entered into the C19-GRA provider registry from Ireland between 24th March 2020 and 31

resultsOf 237 cases included, 59.9% were female, 95 (41.3%) were hospitalised, and 22 (9.3%) died. Hospitalisation was more common with increasing age, gout, smoking, long-term glucocorticoid use, comorbidities, and specific comorbidities of cardiovascular and pulmonary disease, and cancer. Hospitalisation was less frequent in people with inflammatory arthritis and conventional synthetic or biologic disease-modifying antirheumatic drug use. Hospitalisation had a U-shaped relationship with disease activity, being more common in both high disease activity and remission. Mortality was more common with increasing age, gout, smoking, long-term glucocorticoid use, comorbidities, and specific comorbidities of cardiovascular disease, pulmonary disease, and obesity. Inflammatory arthritis was less frequent in those who died.

conclusionHospitalisation or death were more frequently experienced by RMD patients with increasing age, certain comorbidities including potentially modifiable ones, and certain medications and diagnoses amongst other factors. These are important 'indicators' that can help risk-stratify and inform the management of RMD patients.

Indexed as

COVID-19GoutMusculoskeletal DiseasesFemaleGlucocorticoidsHumansIrelandMalePandemicsGlucocorticoidsBiologicsCOVID-19HospitalisationRMD

Identifiers

PMID36622628
PMCPMC9827440
OpenAlexW4313824171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.