Evidence map›Paper›PMID 36622517›Full record

ReviewJournal of gastrointestinal cancer2023

Multi-Disciplinary Management in Rectal Cancer Survivorship: A Clinical Practice Review.

Hilary Chan, Marissa B Savoie, Amir Munir, Javid Moslehi, Mekhail Anwar, Angela Laffan, Tami Rowen, Rebeca Salmon, Madhulika Varma, Katherine Van Loon

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of gastrointestinal cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Sexual dysfunction after colorectal and anal cancer-treatment in nurse-led sexological clinics.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  6. Observational
  7. Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hilary ChanDepartment of Medicine, Division of Hematology and Oncology, University of California, San Francisco (UCSF), 550 16th Street, Floor 06, Room 6803, Box 3211, San Francisco, CA, 94158, USA.
Marissa B SavoieDepartment of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Amir MunirUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Javid MoslehiUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Mekhail AnwarUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Angela LaffanUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Tami RowenDepartment of Obstetrics and Gynecology, UCSF, San Francisco, CA, USA.
Rebeca SalmonUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Madhulika VarmaUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Katherine Van LoonDepartment of Medicine, Division of Hematology and Oncology, University of California, San Francisco (UCSF), 550 16th Street, Floor 06, Room 6803, Box 3211, San Francisco, CA, 94158, USA. katherine.vanloon@ucsf.edu.
UCSF Helen Diller Family Comprehensive Cancer Center · USUniversity of California, San Francisco · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most common cancer in the USA and worldwide. In the USA, nearly one-third of CRC cases are anatomically classified as rectal cancer. Over the past few decades, continued refinement of multimodality treatment and the introduction of new therapeutic agents have enhanced curative treatment rates and quality of life outcomes. As treatments improve and the incidence of young onset rectal cancer rises, the number of rectal cancer survivors grows each year. This trend highlights the growing importance of rectal cancer survivorship. Multimodality therapy with systemic chemotherapy, chemoradiation, and surgery can result in chronic toxicities in multiple organ systems, requiring a multi-disciplinary care model with services ranging from appropriate cancer surveillance to management of long-term toxicities and optimization of modifiable risk factors. Here, we review the evidence on these long-term toxicities and provide management considerations from consensus guidelines. Specific topics include bowel dysfunction from radiation and surgery, oxaliplatin-induced neuropathy, accelerated bone degeneration, the impact of fluoropyrimidines on long-term cardiovascular health, urinary incontinence, sexual dysfunction, and psychosocial distress. Additionally, we review modifiable risk factors to inform providers and rectal cancer survivors of various lifestyle and behavioral changes that can be made to improve their long-term health outcomes.

Indexed as

Cancer SurvivorsRectal NeoplasmsSexual Dysfunction, PhysiologicalHumansQuality of LifeSurvivorshipModifiable risk factorsQuality of lifeRectal cancerSurvivorshipToxicity

Identifiers

PMID36622517
PMCPMC10754749
OpenAlexW4313879945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.