Evidence map›Paper›PMID 36622467›Full record

ArticleMedical molecular morphology2023

Regaining enamel color quality using enamel matrix derivative.

Hiroyuki Sugaya, Yoshihito Kurashige, Kai Suzuki, Sayaka Sakakibara, Yusuke Fujita, Syed Taufiqul Islam, Takashi Nezu, Shuichi Ito, Yoshihiro Abiko, Masato Saitoh

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical molecular morphology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Hiroyuki SugayaDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Yoshihito KurashigeDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Kai SuzukiDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Sayaka SakakibaraDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Yusuke FujitaDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Syed Taufiqul IslamDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan.
Takashi NezuDivision of Biomaterials and Bioengineering, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Shuichi ItoDivision of Dental Education Development, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Yoshihiro AbikoDivision of Oral Medicine and Pathology, Dentistry School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Masato SaitohDivision of Pediatric, Dentistry School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Tobetsu, Ishikari, Hokkaido, 061-0293, Japan. msaitoh@hoku-iryo-u.ac.jp.ORCID http://orcid.org/0000-0002-9237-8363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to demonstrate and compare the accuracy of tooth shade selection due to the remineralized enamel crystal with enamel matrix derivative (EMD) in vitro. Etched enamel slices were immersed in four types of mineralization buffers for 16 h. Sodium fluoride (NaF) was added to final concentrations of 1-100 ppm with the mineralization buffer that demonstrated the highest mineralization efficiency. EMD was added to the mineralization buffer containing NaF to see if it has any remineralization capacities. The remineralized enamel crystal was analyzed by SEM and XRD. The tooth shade was evaluated by CIE L*a*b*. The results showed that, without NaF, plate-like nanocrystals were formed on the enamel surface, but with NaF, needle-like nanocrystals were formed. By adding EMD, a layer of well-compacted hydroxyapatite crystals was successfully precipitated onto the natural enamel surface. No significant differences were observed in the L* value of the mineralization surface pre-etching and after mineralization buffer containing NaF and EMD. A new method has been developed to recover the color quality of enamel, as well as to mineralize the tooth enamel by constructing hydroxyapatite crystals with mineralization buffers containing NaF and EMD on the etched tooth surface.

Indexed as

FluoridesSodium FluorideDental Enamel ProteinsHydroxyapatitesDental Enamel Proteinsenamel matrix proteinsFluoridesHydroxyapatitesSodium FluorideAmelogeninCIE L*a*b*EmdogainHapHydroxyapatite crystalsMineralization buffer

Identifiers

PMID36622467
PMCPMC10188587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.