Evidence map›Paper›PMID 36622349›Full record

ArticleBlood advances2023

Low neutralizing activity of AZD7442 against current SARS-CoV-2 Omicron variants in patients with B-cell malignancies.

Andres Chang, Jean L Koff, Lilin Lai, Victor M Orellana-Noia, Minal Surati, Alyssa M K Leal, Madison L Ellis, Bushra Wali, Alberto Moreno, Susanne L Linderman and 7 more

Abstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andres ChangDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0001-6679-9060
Jean L KoffDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0003-4414-0489
Lilin LaiEmory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.
Victor M Orellana-NoiaDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-0742-1436
Minal SuratiDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0001-7630-4025
Alyssa M K LealDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
Madison L EllisDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-0325-5477
Bushra WaliDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.
Alberto MorenoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.
Susanne L LindermanEmory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0003-3297-3774
Colin B O'LearyDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
Pamela B AllenDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
Michael C ChurnetskiDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
Madhav V DhodapkarDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
Mehul S SutharEmory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-2686-8380
Jonathon B CohenDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-2723-6481
Rafi AhmedEmory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-9591-2621

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI MADHAV V DHODAPKAR · 2009 to 2026
$47.5M
Systems Biological Analysis of Innate and Adaptive Responses to VaccinationU19AI090023 · NIAID · EMORY UNIVERSITY · PI MULLIGAN, MARK JOSEPH · 2010 to 2021
$45.0M
Project-004U54CA260563 · NCI · EMORY UNIVERSITY · PI DHODAPKAR, MADHAV V, SANZ, IGNACIO E. · 2020 to 2024
$10.2M
HARNESSING HOST RESPONSE TO PREVENT MYELOMAR35CA197603 · NCI · YALE UNIVERSITY · PI DHODAPKAR, MADHAV V · 2016 to 2022
$5.8M
NCI NIH HHS P30 CA138292NCI NIH HHS R35 CA197603NCI NIH HHS U54 CA260563NIAID NIH HHS HHSN272201400004CNIAID NIH HHS U19 AI090023NIH HHS HHSN272201400004CNIH HHS P51 OD011132
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19SARS-CoV-2Antibodies, MonoclonalAntibodies, NeutralizingDrug CombinationsHumansAntibodies, MonoclonalAntibodies, Neutralizingcilgavimab and tixagevimab drug combinationDrug Combinations

Identifiers

PMID36622349
PMCPMC9906471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.