Evidence map›Paper›PMID 36622251›Full record

ArticlemSphere2023

Tropodithietic Acid, a Multifunctional Antimicrobial, Facilitates Adaption and Colonization of the Producer, Phaeobacter piscinae.

Laura Louise Lindqvist, Scott A Jarmusch, Eva C Sonnenschein, Mikael Lenz Strube, Janie Kim, Maike Wennekers Nielsen, Paul J Kempen, Erwin M Schoof, Sheng-Da Zhang, Lone Gram

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Iron limitation triggers roseoceramide biosynthesis and membrane remodeling in marine roseobacter.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Co-existence of two antibiotic-producing marine bacteria:Applied and environmental microbiology · 2024
    Article
  11. Antagonistic activity ofApplied and environmental microbiology · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Laura Louise LindqvistDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0001-6591-0767
Scott A JarmuschDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-1021-1608
Eva C SonnenscheinDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0001-6959-5100
Mikael Lenz StrubeDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0003-0905-5705
Janie KimDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0001-5600-7613
Maike Wennekers NielsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Paul J KempenNational Centre for Nano Fabrication and Characterization, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0003-2179-2257
Erwin M SchoofDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-3117-7832
Sheng-Da ZhangDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-2220-3904
Lone GramDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-1076-5723
Technical University of Denmark · DKPrinceton University · USSwansea University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the marine environment, surface-associated bacteria often produce an array of antimicrobial secondary metabolites, which have predominantly been perceived as competition molecules. However, they may also affect other hallmarks of surface-associated living, such as motility and biofilm formation. Here, we investigate the ecological significance of an antibiotic secondary metabolite, tropodithietic acid (TDA), in the producing bacterium, Phaeobacter piscinae S26. We constructed a markerless in-frame deletion mutant deficient in TDA biosynthesis, S26Δ

Indexed as

RhodobacteraceaeType IV Secretion SystemsAnti-Bacterial AgentsTropoloneAnti-Bacterial Agentstropodithietic acidTropoloneType IV Secretion Systemsbiofilmgene transfer agenthorizontal gene transfermotilityniche colonizationPhaeobacterprophagesecondary metabolitestropodithietic acid

Identifiers

PMID36622251
PMCPMC9942592
OpenAlexW4313877311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.