Evidence map›Paper›PMID 36622099›Full record

ArticleeLife2023

Cryo-EM structures of mitochondrial respiratory complex I from

Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Cryo-EM single-particle analysis expanding towards increasingly native samples.Acta crystallographica. Section D, Structural biology · 2025
    Review
  11. Global conformations ofScience advances · 2025
    Article
  12. Low oxidative stress during mitochondrial recovery from anoxia in Artemia franciscana, an invertebrate extremophile.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025
    Article
  13. bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. High-resolutionbioRxiv : the preprint server for biology · 2024
    Article
  20. Using cryo-EM to understand the assembly pathway of respiratory complex I.Acta crystallographica. Section D, Structural biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ahmed-Noor A Agip *The Medical Research Council Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, United Kingdom.ORCID 0000-0002-3020-8262
Injae Chung *The Medical Research Council Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, United Kingdom.ORCID 0000-0002-2902-4677
Alvaro Sanchez-Martinez *The Medical Research Council Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, United Kingdom.ORCID 0000-0002-2728-6251
Alexander J WhitworthThe Medical Research Council Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, United Kingdom.ORCID 0000-0002-1154-6629
Judy HirstThe Medical Research Council Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, United Kingdom.ORCID 0000-0001-8667-6797
MRC Mitochondrial Biology Unit · GB

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Medical Research Council MC_UU_00015/2Medical Research Council MC_UU_00015/6Medical Research Council MC_UU_00028/1Medical Research Council MC_UU_00028/6NIH HHS P40 OD018537
6 · The paper itself

Abstract

Respiratory complex I powers ATP synthesis by oxidative phosphorylation, exploiting the energy from NADH oxidation by ubiquinone to drive protons across an energy-transducing membrane.

Indexed as

Drosophila melanogasterElectron Transport Complex IAnimalsCryoelectron MicroscopyMitochondriaUbiquinoneElectron Transport Complex IUbiquinoneD. melanogasterenzyme mechanismmitochondriamolecular biophysicsNADH:ubiquinone oxidoreductaseoxidative phosphorylationstructural biology

Identifiers

PMID36622099
PMCPMC9977279
OpenAlexW4313828871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.