Evidence map›Paper›PMID 36622085›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023

Age at natural menopause impacts cerebrovascular reactivity and brain structure.

M Erin Moir, Adam T Corkery, Katherine A Senese, Kathleen B Miller, Andrew G Pearson, Nicole A Loggie, Anna J Howery, Sarean H A Sumner, Karly A Cody, Laura B Eisenmenger and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Effects of dietary soy content on cerebral artery function and behavior in ovariectomized female mice.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

M Erin MoirBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Adam T CorkeryBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Katherine A SeneseBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Kathleen B MillerBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0003-2878-3978
Andrew G PearsonBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0002-3908-936X
Nicole A LoggieBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Anna J HoweryBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Sarean H A SumnerBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Karly A CodyWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Laura B EisenmengerDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0001-6764-4239
Sterling C JohnsonWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jill N BarnesBruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0001-6317-4153
University of Wisconsin–Madison · US

Funding

Wisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Henrik Zetterberg · 2019 to 2026
$34.5M
Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Cerebral blood flow, connectivity and cognition: the effect of age and exerciseR00HL118154 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BARNES, JILL NICOLE · 2015 to 2017
$735k
Cerebral blood flow, connectivity and cognition: the effect of age and exerciseK99HL118154 · NHLBI · MAYO CLINIC ROCHESTER · PI BARNES, JILL NICOLE · 2014 to 2015
$180k
NHLBI NIH HHS K99 HL118154NHLBI NIH HHS R00 HL118154NHLBI NIH HHS T32 HL007936NIA NIH HHS P30 AG062715
6 · The paper itself

Abstract

Menopause is associated with adverse changes in vascular health coinciding with an increased risk of stroke and vascular cognitive impairment. However, there is significant variation in the age at menopause. The present study examined how the age at natural menopause impacts cerebrovascular reactivity and structural biomarkers of brain aging. Thirty-five healthy postmenopausal women were classified as early-onset menopause (Early;

Indexed as

BrainCerebrovascular CirculationBlood Flow VelocityCarbon DioxideFemaleHumansHypercapniaMenopauseCarbon Dioxidebrain volumecerebrovascular reactivitymenopausewhite matter hyperintensities

Identifiers

PMID36622085
PMCPMC9886341
OpenAlexW4313857300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.