Evidence map›Paper›PMID 36622063›Full record

ArticleBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia2023

Diabetic macular edema treatment with subthreshold micropulse laser - five-year long monitoring.

Martina Zavorkova, Jana Nekolova, Lidmila Prochazkova, Eva Cermakova, Nada Jiraskova

Open access · goldAbstract read
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In one paragraph

Article in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Martina ZavorkovaDepartment of Ophthalmology, Faculty of Health Studies, Jan Evangelista Purkyne University and Department of Ophthalmology, Masaryk Hospital, Usti nad Labem, Krajska zdravotni a.s., Usti nad Labem, Czech Republic.
Jana NekolovaDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, Charles University and Department of Ophthalmology, University Hospital Hradec Kralove, Czech Republic.
Lidmila ProchazkovaDepartment of Ophthalmology, Faculty of Health Studies, Jan Evangelista Purkyne University and Department of Ophthalmology, Masaryk Hospital, Usti nad Labem, Krajska zdravotni a.s., Usti nad Labem, Czech Republic.
Eva CermakovaDepartment of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Nada JiraskovaDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, Charles University and Department of Ophthalmology, University Hospital Hradec Kralove, Czech Republic.
University Hospital Hradec Králové · CZCharles University · CZKrajská Zdravotní · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of this study was to evaluate the efficacy of diabetic macular edema (DME) therapy using subthreshold micropulse laser (SMPL) with a wavelength of 577 nm during a long-term monitoring period of 5 years.

methodsThe cohort included the total number of 52 eyes of 34 patients with DME. All underwent the standard laser treatment for the diabetic retinopathy outside the macula and DME treatment with SMPL. Subsequent check-ups were followed every 3 months in the first year of treatment, and every 4 to 6 months in the following years. The treatment was combined neither with focal macular laser nor with anti-VEGF therapy.

resultsThe mean central retinal thickness (CRT) was 345.9 µm SD 122.6 µm at the beginning of the monitoring. At the end of the follow-up period five years after treatment it was 256.4 µm SD 98.4 µm. The mean CRT decreased by 89.5 µm SD 153.6 µm during 5 years. At the beginning of the monitoring, before treatment with SMPL, the best corrected visual acuity (BCVA) was 70.0, SD 10.1 ETDRS letters. One year after therapy, BCVA was 72, SD 10.0 letters, two years later it was 71.4, SD 10.4 letters and decreased to 66.9, SD 12.1 letters after 5 years. The mean BCVA decreased by merely 3.1, SD 10.9 letters during 5 years.

conclusionBased on our long-term observations, the DME treatment with SMPL appears to be an effective method for reducing DME and protecting BCVA against rapid worsening.

Indexed as

Diabetes MellitusDiabetic RetinopathyMacula LuteaMacular EdemaHumansLaser CoagulationLasersTomography, Optical CoherenceTreatment Outcomediabetic macular edemasubthreshold micropulse laser therapy

Identifiers

PMID36622063
OpenAlexW4313877897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.