Evidence map›Paper›PMID 36622042›Full record

ReviewToxicological sciences : an official journal of the Society of Toxicology2023

Air pollution and respiratory infections: the past, present, and future.

Alexys Monoson, Evangeline Schott, Kerry Ard, Brita Kilburg-Basnyat, Robert M Tighe, Sonal Pannu, Kymberly M Gowdy

Open access · bronzeAbstract readReview
In one paragraph

Review in Toxicological sciences : an official journal of the Society of Toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Association between long-term PMBMC public health · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Ambient Air Pollution and COVID-19 in California.Research report (Health Effects Institute) · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Natural Experiments: An Efficient Tool for Population Respiratory Health Evaluation.American journal of respiratory and critical care medicine · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Alexys MonosonDepartment of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210, USA.
Evangeline SchottDepartment of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210, USA.
Kerry ArdSchool of Environment and Natural Resources, The Ohio State University, Columbus, Ohio 43210, USA.
Brita Kilburg-BasnyatDepartment of Pharmacology and Toxicology, East Carolina University, Greenville, North Carolina 27834, USA.
Robert M TigheDepartment of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
Sonal PannuDepartment of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210, USA.
Kymberly M GowdyDepartment of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210, USA.
The Ohio State University Wexner Medical Center · USDuke Medical Center · USEast Carolina University · USThe Ohio State University · US

Funding

USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE · 1999 to 2026
$17.9M
CXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1M
Novel role for CD163 in ozone induced alterations of pulmonary immunityR01ES028829 · NIEHS · OHIO STATE UNIVERSITY · PI GOWDY, KYMBERLY MAE · 2018 to 2022
$2.7M
NIA NIH HHS P30 AG017265NIEHS NIH HHS R01 ES027574NIEHS NIH HHS R01 ES028829
6 · The paper itself

Abstract

Air pollution levels across the globe continue to rise despite government regulations. The increase in global air pollution levels drives detrimental human health effects, including 7 million premature deaths every year. Many of these deaths are attributable to increased incidence of respiratory infections. Considering the COVID-19 pandemic, an unprecedented public health crisis that has claimed the lives of over 6.5 million people globally, respiratory infections as a driver of human mortality is a pressing concern. Therefore, it is more important than ever to understand the relationship between air pollution and respiratory infections so that public health measures can be implemented to ameliorate further morbidity and mortality. This article aims to review the current epidemiologic and basic science research on interactions between air pollution exposure and respiratory infections. The first section will present epidemiologic studies organized by pathogen, followed by a review of basic science research investigating the mechanisms of infection, and then conclude with a discussion of areas that require future investigation.

Indexed as

Air PollutantsAir PollutionCOVID-19Respiratory Tract InfectionsHumansPandemicsParticulate MatterPublic HealthAir PollutantsParticulate Matterair pollutionCOVID-19inflammationlungpneumonia

Identifiers

PMID36622042
PMCPMC10025881
OpenAlexW4313857594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.