SynthesisInternational journal of stroke : official journal of the International Stroke Society2023
Association of post-stroke fatigue with physical activity and physical fitness: A systematic review and meta-analysis.
Synthesis in International journal of stroke : official journal of the International Stroke Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Optimizing physical fitness in chronic stroke patients: the impact of exercise training modality and dosage on maximal and sub-maximal fitness - a systematic review and meta-analysis.Journal of rehabilitation medicine · 2025Pooled it
- Neuroimaging correlates of post-stroke fatigue: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Optimal exercise prescription for balance after stroke: a Bayesian dose-response network meta-analysis.Frontiers in neurologyPooled it
- Trial
- Objective physical activity characteristics and long-term functional disability trajectories in community-dwelling older adults: the amplifying risk of stroke.Frontiers in public health · 2026Article
- Physical Activity Interventions for Patients With Poststroke Fatigue: Protocol for a Scoping Review.JMIR research protocols · 2025Article
- The relationship between fatigue and insomnia in ischemic stroke convalescence patients: the chained mediation effects of social support and anxiety.BMC neurology · 2025Article
- Analysis of factors influencing poor neurological outcomes in patients with acute ischemic stroke.Annals of medicine · 2025Article
- Narrative Review on Post-Stroke Outcomes Through Recognition of Frailty, Sarcopenia, and Palliative Care Needs.Healthcare (Basel, Switzerland) · 2025Review
- Interrelationship between fatigue and recovery of physical function in stroke survivors: a longitudinal mixed-methods study.European journal of physical and rehabilitation medicine · 2025Article
- Self-reported physical activity more than 1 year after stroke and its determinants in relation to the WHO recommendations.PM & R : the journal of injury, function, and rehabilitation · 2025Article
- Joint effects of physical activity and sleep quality on all-cause and cardiovascular disease mortality in stroke survivors: a population-based cohort study from the UK-Biobank.BMC public health · 2025Article
- Experiences of participation in cardiorespiratory training among people with post-stroke fatigue: a qualitative study.Journal of rehabilitation medicine · 2025Article
- Differences in symptom clusters based on multidimensional symptom experience and symptom burden in stroke patients.Scientific reports · 2025Article
- Adherence to exercise in breast cancer survivors during and after active treatment: A systematic review and meta-analysis.JSAMS plus · 2024Review
- Post-stroke fatigue interventions for stroke survivors: A scoping review.Belitung nursing journal · 2024Article
- Is Cardiorespiratory Fitness Independently Associated with Fatigue in Patients with Transient Ischemic Attack or Minor Stroke?Brain sciences · 2023Article
- Pathophysiology and Management of Fatigue in Neuromuscular Diseases.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt has been hypothesized that post-stroke fatigue (PSF) is associated with reduced physical activity (PA) and impaired physical fitness (fitness). Understanding associations between PSF and PA, and/or fitness could help guide the development of targeted exercise interventions to treat PSF.
aimsOur systematic review and meta-analysis aimed to investigate PSF's associations with PA and fitness. SUMMARY OF REVIEW: Following a registered protocol, we included studies with cross-sectional or prospective observational designs, published in English or a Scandinavian language, which reported an association of PSF with PA and/or fitness in adult stroke survivors. We searched MEDLINE, Embase, AMED, CINAHL, PsycINFO, ClinicalTrials.gov, and World Health Organization's International Clinical Trials Registry Platform from inception to November 30, 2022. Risk of bias was assessed using Quality in Prognosis Studies. Thirty-two unique studies (total n = 4721 participants, 55% male), and three study protocols were included. We used random-effects meta-analysis to pool data for PA and fitness outcomes, and vote-counting of direction of association to synthesize data that could not be meta-analyzed. We found moderate-certainty evidence of a weak association between higher PSF and impaired fitness (meta
conclusionsThe meta-analysis showed moderate-certainty evidence of an association between higher PSF and impaired fitness. These results indicate that fitness might protect against PSF. Larger prospective studies and randomized controlled trials evaluating the effect of exercise on PSF are needed to confirm these findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.