Evidence map›Paper›PMID 36621919›Full record

ArticleeLife2023

Interdependent progression of bidirectional sister replisomes in

Po Jui Chen, Anna B McMullin, Bryan J Visser, Qian Mei, Susan M Rosenberg, David Bates

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Po Jui ChenMolecular Virology and Microbiology, Baylor College of Medicine, Houston, United States.
Anna B McMullinMolecular Virology and Microbiology, Baylor College of Medicine, Houston, United States.
Bryan J VisserGraduate Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, United States.
Qian MeiSystems, Synthetic, and Physical Biology Program, Rice University, Houston, United States.
Susan M RosenbergMolecular Virology and Microbiology, Baylor College of Medicine, Houston, United States.
David BatesMolecular Virology and Microbiology, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-0870-055X
Baylor College of Medicine · USRice University · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
Mechanisms of Endogenous DNA Damage PromotionR01CA250905 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MILLER, KYLE M, ROSENBERG, SUSAN M · 2020 to 2024
$3.3M
MOLECULAR MECHANISMS OF STRESS-INDUCED MUTATIONR35GM122598 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ROSENBERG, SUSAN M · 2017 to 2020
$2.4M
Dynamics and regulation of sister chromosome cohesion in E. coli.R01GM102679 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BATES, DAVID · 2012 to 2016
$1.5M
Dynamics and regulation of sister chromosome cohesion in E. coliR01GM135368 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BATES, DAVID · 2020 to 2021
$690k
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA250905NCRR NIH HHS S10 RR024574NIGMS NIH HHS R01 GM102679NIGMS NIH HHS R01 GM135368NIGMS NIH HHS R35 GM122598NIH HHS R01 GM102679NIH HHS R01 GM135368NIH HHS R35 GM122598
6 · The paper itself

Abstract

Bidirectional DNA replication complexes initiated from the same origin remain colocalized in a factory configuration for part or all their lifetimes. However, there is little evidence that sister replisomes are functionally interdependent, and the consequence of factory replication is unknown. Here, we investigated the functional relationship between sister replisomes in

Indexed as

DNA ReplicationEscherichia coliChromosomesDNADNA-Binding ProteinsDNADNA-Binding ProteinsE. coligeneticsgenomicsinfectious diseasemicrobiologyreplication factoryreplication fork progressionreplication fork stallingreplisome dynamicsreplisome localization

Identifiers

PMID36621919
PMCPMC9859026
OpenAlexW4313857739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.