Evidence map›Paper›PMID 36621812›Full record

ArticleMedical physics2023

Modeling linear accelerator (Linac) beam data by implicit neural representation learning for commissioning and quality assurance applications.

Lianli Liu, Liyue Shen, Yong Yang, Emil Schüler, Wei Zhao, Gordon Wetzstein, Lei Xing

Abstract read
In one paragraph

Article in Medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lianli LiuDepartment of Radiation Oncology, Stanford University, Palo Alto, California, USA.
Liyue ShenDepartment of Electrical Engineering, Stanford University, Palo Alto, California, USA.
Yong YangDepartment of Radiation Oncology, Stanford University, Palo Alto, California, USA.
Emil SchülerDepartment of Radiation Oncology, Stanford University, Palo Alto, California, USA.
Wei ZhaoDepartment of Radiation Oncology, Stanford University, Palo Alto, California, USA.
Gordon WetzsteinDepartment of Electrical Engineering, Stanford University, Palo Alto, California, USA.
Lei XingDepartment of Radiation Oncology, Stanford University, Palo Alto, California, USA.

Funding

Dual Modality X-ray Luminescence CT for in vivo Cancer ImagingR01CA227713 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2019 to 2023
$2.9M
Radioluminescence dosimetry solution for precision radiation therapyR01CA223667 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2018 to 2022
$2.4M
DASSIM-RT and Compressed Sensing-Based Inverse PlanningR01CA176553 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2014 to 2018
$2.4M
Leveraging deep learning for markerless motion management in radiation therapyR01CA256890 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2021 to 2025
$2.1M
Development of AI-Augmented quality assurance tools for radiation therapyR01CA275772 · NCI · STANFORD UNIVERSITY · PI Lei Xing · 2023 to 2026
$2.1M
NCI NIH HHS R01 CA176553NCI NIH HHS R01 CA223667NCI NIH HHS R01 CA227713NCI NIH HHS R01 CA256890NCI NIH HHS R01 CA275772NIH HHS 1R01CA176553NIH HHS 1R01CA223667NIH HHS 1R01CA227713
6 · The paper itself

Abstract

backgroundLinear accelerator (Linac) beam data commissioning and quality assurance (QA) play a vital role in accurate radiation treatment delivery and entail a large number of measurements using a variety of field sizes. How to optimize the effort in data acquisition while maintaining high quality of medical physics practice has been sought after. PURPOSE: We propose to model Linac beam data through implicit neural representation (NeRP) learning. The potential of the beam model in predicting beam data from sparse measurements and detecting data collection errors was evaluated, with the goal of using the beam model to verify beam data collection accuracy and simplify the commissioning and QA process. MATERIALS AND

methodsNeRP models with continuous and differentiable functions parameterized by multilayer perceptrons (MLPs) were used to represent various beam data including percentage depth dose (PDD) and profiles of 6 MV beams with and without flattening filter. Prior knowledge of the beam data was embedded into the MLP network by learning the NeRP of a vendor-provided "golden" beam dataset. The prior-embedded network was then trained to fit clinical beam data collected at one field size and used to predict beam data at other field sizes. We evaluated the prediction accuracy by comparing network-predicted beam data to water tank measurements collected from 14 clinical Linacs. Beam datasets with intentionally introduced errors were used to investigate the potential use of the NeRP model for beam data verification, by evaluating the model performance when trained with erroneous beam data samples.

resultsLinac beam data predicted by the model agreed well with water tank measurements, with averaged Gamma passing rates (1%/1 mm passing criteria) higher than 95% and averaged mean absolute errors less than 0.6%. Beam data samples with measurement errors were revealed by inconsistent beam predictions between networks trained with correct versus erroneous data samples, characterized by a Gamma passing rate lower than 90%.

conclusionA NeRP beam data modeling technique has been established for predicting beam characteristics from sparse measurements. The model provides a valuable tool to verify beam data collection accuracy and promises to simplify commissioning/QA processes by reducing the number of measurements without compromising the quality of medical physics service.

Indexed as

Radiotherapy, Intensity-ModulatedParticle AcceleratorsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedWaterWaterbeam data modelingLinac commissioningmachine learningquality assurance

Identifiers

PMID36621812
PMCPMC10175132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.