Evidence map›Paper›PMID 36621552›Full record

ArticleJournal of neuroscience methods2023

Visiomode: An open-source platform for building rodent touchscreen-based behavioral assays.

Constantinos Eleftheriou, Thomas Clarke, V Poon, Marie Zechner, Ian Duguid

Abstract read
In one paragraph

Article in Journal of neuroscience methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Constantinos EleftheriouSimons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XD, UK; Centre for Discovery Brain Sciences and Patrick Wild Centre, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK. Electronic address: Constantinos.Eleftheriou@ed.ac.uk.
Thomas ClarkeCentre for Discovery Brain Sciences and Patrick Wild Centre, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
V PoonCentre for Discovery Brain Sciences and Patrick Wild Centre, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
Marie ZechnerThe Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, Scotland, UK.
Ian DuguidSimons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XD, UK; Centre for Discovery Brain Sciences and Patrick Wild Centre, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK. Electronic address: Ian.Duguid@ed.ac.uk.

Funding

Medical Research Council MR/W004577/1Wellcome TrustWellcome Trust 110131/Z/15/Z
6 · The paper itself

Abstract

backgroundTouchscreen-based behavioral assays provide a robust method for assessing cognitive behavior in rodents, offering great flexibility and translational potential. The development of touchscreen assays presents a significant programming and mechanical engineering challenge, where commercial solutions can be prohibitively expensive and open-source solutions are underdeveloped, with limited adaptability. NEW

methodHere, we present Visiomode (www.visiomode.org), an open-source platform for building rodent touchscreen-based behavioral tasks. Visiomode leverages the inherent flexibility of touchscreens to offer a simple yet adaptable software and hardware platform. The platform is built on the Raspberry Pi computer combining a web-based interface and powerful plug-in system with an operant chamber that can be adapted to generate a wide range of behavioral tasks.

resultsAs a proof of concept, we use Visiomode to build both simple stimulus-response and more complex visual discrimination tasks, showing that mice display rapid sensorimotor learning including switching between different motor responses (i.e., nose poke versus reaching). COMPARISON WITH EXISTING

methodsCommercial solutions are the 'go to' for rodent touchscreen behaviors, but the associated costs can be prohibitive, limiting their uptake by the wider neuroscience community. While several open-source solutions have been developed, efforts so far have focused on reducing the cost, rather than promoting ease of use and adaptability. Visiomode addresses these unmet needs providing a low-cost, extensible platform for creating touchscreen tasks.

conclusionsDeveloping an open-source, rapidly scalable and low-cost platform for building touchscreen-based behavioral assays should increase uptake across the science community and accelerate the investigation of cognition, decision-making and sensorimotor behaviors both in health and disease.

Indexed as

LearningRodentiaAnimalsCognitionComputersMiceSoftwareBehaviorOpen-sourceRodentSensorimotorTouchscreenVisiomode

Identifiers

PMID36621552
PMCPMC10375831

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.