Evidence map›Paper›PMID 36621521›Full record

ArticleJournal of diabetes2023

Changes in cardiovascular risk factors among children and young adults with type 1 diabetes during the COVID-19 pandemic compared to previous years-Results from the German DPV registry.

Alexander J Eckert, Sabine Linke, Karl-Otfried Schwab, Thekla von dem Berge, Eckhard Schönau, Ibrahim Duran, Axel Dost, Christine Joisten, Heike Bartelt, Katarina Braune and 2 more

Abstract read
In one paragraph

Article in Journal of diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Endocrine manifestations of COVID-19 in children: A scoping review.Best practice & research. Clinical endocrinology & metabolism · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander J EckertInstitute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.ORCID https://orcid.org/0000-0003-1239-3078
Sabine LinkeKatholisches Kinderkrankenhaus WILHELMSTIFT gGmbH, Children's Hospital, Hamburg, Germany.
Karl-Otfried SchwabFaculty of Medicine, Centre for Pediatrics and Adolescent Medicine, Division of Pediatric Diabetology, Endocrinology and Lipidology, Medical Centre, University of Freiburg, Freiburg, Germany.
Thekla von dem BergeDiabetes Centre for Children and Adolescents, Children's Hospital Auf der Bult, Hannover, Germany.
Eckhard SchönauFaculty of Medicine and University Hospital, Department of Pediatrics, University of Cologne, Cologne, Germany.
Ibrahim DuranFaculty of Medicine and University Hospital, Centre of Prevention and Rehabilitation, Uni Reha, University of Cologne, Cologne, Germany.
Axel DostDepartment of Pediatrics, University Hospital Jena, Jena, Germany.
Christine JoistenDepartment for Physical Activity in Public Health, Institute of Movement and Neurosciences, German Sport University Cologne, Cologne, Germany.
Heike BarteltDepartment of Endocrinology and Diabetology, University of Leipzig, Hospital for Children and Adolescents, Leipzig, Germany.
Katarina BrauneInstitute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Joachim RosenbauerGerman Centre for Diabetes Research (DZD), Neuherberg, Germany.
Reinhard W HollInstitute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.

Funding

Deutsche Diabetes GesellschaftGerman Centre for Diabetes Research (DZD) 82DZD14E03German Diabetes Foundation (DDS) FP-0446-2022German Federal Ministry for Education and ResearchGerman Robert Koch Institute (RKI)
6 · The paper itself

Abstract

backgroundThe diverse stages of the COVID-19 pandemic led to several social circumstances that influenced daily life and health behavior. PURPOSE: To evaluate changes in cardiovascular risk factors and physical activity among children and young adults with type 1 diabetes (T1D) during the COVID-19 pandemic in Germany compared to previous years.

methodsA total of 32 785 individuals aged 6-21 years at baseline with T1D from the German diabetes patient follow-up (DPV) registry contributed data on 101 484 person-years between 2016 and 2021. The first treatment year of each individual within this period was considered as baseline. Based on trends from 2016 to 2019, we estimated differences in body mass index-SD score (BMI-SDS), blood pressure (BP-SDS), and lipid levels (non-high-density lipoprotein [non-HDL]) between observed and predicted estimates for the years 2020 and 2021 using linear regression analysis standardized for age, diabetes duration, sex, and migratory background. The proportion doing organized sports and smoking cigarettes was analyzed using multivariable logistic regression models.

resultsBMI-SDS increased constantly from 2016 to 2021 without a significant increase above expected values for 2020/2021. Systolic BP-SDS (difference observed vs. expected with 95% confidence interval, 2020: 0.10 [0.07-0.14], 2021: 0.17 [0.14-0.20]) and non-HDL (2020: 2.7 [1.3-4.1] mg/dl, 2021: 4.1 [2.7-5.5] mg/dl) were significantly increased (all p < .001) in both pandemic years. The proportion of subjects participating in organized sports was reduced from over 70% in prepandemic years to 35%-65% in diverse stages/waves of the COVID-19 pandemic. The percentage smoking cigarettes did not change.

conclusionsWe describe an increase in BP and atherogenic lipid levels coinciding with a reduction in physical activity but no acceleration of the prepandemic increases in BMI-SDS among young people with T1D during the COVID-19 pandemic.

Indexed as

Cardiovascular DiseasesCOVID-19Diabetes Mellitus, Type 1AdolescentBody Mass IndexChildHeart Disease Risk FactorsHumansLipidsPandemicsRegistriesRisk FactorsYoung AdultLipidsblood pressurecholesterolcoronaviruslipidphysical activitysports体力活动冠状病毒胆固醇血压血脂运动

Identifiers

PMID36621521
PMCPMC9870744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.