Evidence map›Paper›PMID 36621278›Full record

ArticleWater research2023

Global assessment of chemical quality of drinking water: The case of trihalomethanes.

Cristina M Villanueva, Iro Evlampidou, Fathelrahman Ibrahim, Carolina Donat-Vargas, Antonia Valentin, Anca-Maria Tugulea, Shinya Echigo, Dragana Jovanovic, Albert T Lebedev, Mildred Lemus-Pérez and 20 more

Abstract read
In one paragraph

Article in Water research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Chlorine-UV hybrid disinfection: a review on mechanisms and efficiency towards emerging pollutants.Environmental science and pollution research international · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. US drinking water quality: exposure risk profiles for seven legacy and emerging contaminants.Journal of exposure science & environmental epidemiology · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Cristina M VillanuevaISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain; CIBER epidemiología y salud pública (CIBERESP), Av. Monforte de Lemos, 3-5, Madrid 28029, Spain; Universitat Pompeu Fabra (UPF), Doctor Aiguader 88, Barcelona 08003, Spain; IMIM (Hospital del Mar Medical Research Institute), Doctor Aiguader 88, Barcelona 08003, Spain. Electronic address: cristina.villanueva@isglobal.org.
Iro EvlampidouISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain.
Fathelrahman IbrahimISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain.
Carolina Donat-VargasISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain; CIBER epidemiología y salud pública (CIBERESP), Av. Monforte de Lemos, 3-5, Madrid 28029, Spain; Universitat Pompeu Fabra (UPF), Doctor Aiguader 88, Barcelona 08003, Spain.
Antonia ValentinISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain; CIBER epidemiología y salud pública (CIBERESP), Av. Monforte de Lemos, 3-5, Madrid 28029, Spain; Universitat Pompeu Fabra (UPF), Doctor Aiguader 88, Barcelona 08003, Spain.
Anca-Maria TuguleaEnvironmental Health Science and Research Bureau, Health Canada, Ottawa, ON K1A 0K9, Canada.
Shinya EchigoGraduate School of Global Environmental Studies, Kyoto University, Rm252, Research Building 3, Yoshidahonmachi, Sakyo, Kyoto 606-8501, Japan.
Dragana JovanovicDepartment on Drinking Water Quality, Institute of Public Health of Serbia, Dr Subotica 5, Belgrade 11000, Serbia.
Albert T LebedevOrganic Chemistry Department, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.
Mildred Lemus-PérezDepartamento de Ingeniería Civil y Ambiental, Universidad de los Andes, Cra. 1 Este #19a-40, Edificio Mario Laserna - Piso6 Bogotá, 111711, Colombia.
Manuel Rodriguez-SusaDepartamento de Ingeniería Civil y Ambiental, Universidad de los Andes, Cra. 1 Este #19a-40, Edificio Mario Laserna - Piso6 Bogotá, 111711, Colombia.
Arben LuzatiEnvironmental Health Department, Institute of Public Health, Alexander Moisiu Nr. 80, Tirana, Albania.
Telma de Cássia Dos Santos NeryDivisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 44, São Paulo (SP) 05403-900, Brazil.
Pablo A PasténDepartamento de Ingeniería Hidráulica y Ambiental, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna, Macul, Santiago 4860, Chile; Centro de Desarrollo Urbano Sustentable (CEDEUS), Av. Vicuña Mackenna, Macul, Santiago 4860, Chile.
Marisa QuiñonesQuiñones Consulting, Colón 110-1301, Miraflores, Lima 15074, Peru.
Stig RegliOffice of Ground Water and Drinking Water, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave, N.W., Washington, DC 20460, USA.
Richard WeismanOffice of Ground Water and Drinking Water, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave, N.W., Washington, DC 20460, USA.
Shaoxia DongDepartment of Water Quality and Health Monitoring, National Institute of Environmental Health, China CDC, 29# Nanwei Road, Xicheng District, Beijing 100050, PR China.
Mina HaDepartment of Preventive Medicine, Dankook University College of Medicine, 119 Dandae-ro Cheonan-si, Chungnam-do 31116, South Korea.
Songkeart PhattarapattamawongDepartment of Environmental Engineering, King Mongkut's University of Technology Thonburi, 126 Pracha-Utit Rd., Bangmod, Tungkru, Bangkok 10140 Thailand.
Tarek ManasfiEawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf CH-8600, Switzerland.
Shaibu-Imodagbe Egbenya MusahAhmadu Bello University, Samaru Campus, Zaria, Kaduna State, Nigeria.
Amanda EngResearch Centre for Hauora and Health, Massey University, Wellington Campus, PO Box 756, Wellington 6140, New Zealand.
Karel JanákNorwegian Institute of Public Health, P.O. Box 4404 Nydalen, Oslo NO-0456, Norway.
Samantha C RushDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208, USA.
David ReckhowDepartment of Civil and Environmental Engineering, University of Massachusetts, Amherst, MA 01062, USA.
Stuart W KrasnerMetropolitan Water District of Southern California, Water Quality Laboratory, 700 Moreno Ave La Verne, California 91750, USA.
Paolo VineisMRC Centre for Environment and Health, School of Public Health, Imperial College London, Michael Uren Biomedical Engineering Hub, White City Campus, Wood Lane, London W12 0BZ, UK.
Susan D RichardsonDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208, USA.
Manolis KogevinasISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain; CIBER epidemiología y salud pública (CIBERESP), Av. Monforte de Lemos, 3-5, Madrid 28029, Spain; Universitat Pompeu Fabra (UPF), Doctor Aiguader 88, Barcelona 08003, Spain; IMIM (Hospital del Mar Medical Research Institute), Doctor Aiguader 88, Barcelona 08003, Spain.

Funding

Medical Research Council MR/S019669/1
6 · The paper itself

Abstract

backgroundTrihalomethanes (THM), a major class of disinfection by-products, are widespread and are associated with adverse health effects. We conducted a global evaluation of current THM regulations and concentrations in drinking water.

methodsWe included 120 countries (∼7000 million inhabitants in 2016), representing 94% of the world population. We searched for country regulations and THM routine monitoring data using a questionnaire addressed to referent contacts. Scientific and gray literature was reviewed where contacts were not identified or declined participation. We obtained or estimated annual average THM concentrations, weighted to the population served when possible.

resultsDrinking water regulations were ascertained for 116/120 (97%) countries, with 89/116 (77%) including THM regulations. Routine monitoring was implemented in 47/89 (53%) of countries with THM regulations. THM data with a varying population coverage was obtained for 69/120 (58%) countries consisting of ∼5600 million inhabitants (76% of world's population in 2016). Population coverage was ≥90% in 14 countries, mostly in the Global North, 50-89% in 19 countries, 11-49% among 21 countries, and ≤10% in 14 countries including India, China, Russian Federation and Nigeria (40% of world's population). DISCUSSION: An enormous gap exists in THM regulatory status, routine monitoring practice, reporting and data availability among countries, especially between high- vs. low- and middle-income countries (LMICs). More efforts are warranted to regulate and systematically assess chemical quality of drinking water, centralize, harmonize, and openly report data, particularly in LMICs.

Indexed as

Drinking WaterWater Pollutants, ChemicalDisinfectionTrihalomethanesWater SupplyDrinking WaterTrihalomethanesWater Pollutants, ChemicalChemicalsDisinfection by productsDrinking waterInternationalQualityRegulationRoutine monitoringTrihalomethanes

Identifiers

PMID36621278
PMCPMC11372340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.