Evidence map›Paper›PMID 36620767›Full record

ArticleFrontiers in aging neuroscience2022

The role of ethnicity, biological sex, and psychotropic agents in early and late onset Alzheimer's disease.

Alyssa Miller, Ashna Desai, Laurie Theriot Roley, Richard L Goodwin, Adebobola I Nathaniel, Thomas I Nathaniel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alyssa MillerDepartment of Biology, North Greenville University, Tigerville, SC, United States.
Ashna DesaiDepartment of Biology, University of South Carolina, Columbia, SC, United States.
Laurie Theriot RoleyDepartment of Geriatric Medicine, Prisma Health, Greer, SC, United States.
Richard L GoodwinSchool of Medicine Greenville, University of South Carolina, Greenville, SC, United States.
Adebobola I NathanielDepartment of Biology, North Greenville University, Tigerville, SC, United States.
Thomas I NathanielSchool of Medicine Greenville, University of South Carolina, Greenville, SC, United States.
University of South Carolina · USNorth Greenville University · USPrisma Health · US

Funding

Promoting diversity in research training and mentoring for underrepresented minority Students (URM).R25AG067934 · NIA · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NATHANIEL, THOMAS I · 2020 to 2024
$1.8M
NIA NIH HHS R25 AG067934
6 · The paper itself

Abstract

Objective: This study investigates differences in pharmacological and demographic factors among male and female patients with Late-onset Alzheimer's disease (LOAD) and Early-onset Alzheimer's disease (EOAD). Method: Data are from 10,126 AD patients, 9,290 were diagnosed with LOAD, while 836 were diagnosed with EOAD. Data were collected from the Prisma Health Upstate Alzheimer's patients' registry between 2016 and 2021. The logistic regression analysis was used to assess the association between pharmacological and demographic factors in males and females with LOAD and EOAD. Results: In the adjusted analysis for males, patients that were administered memantine [odd ratio (OR) = 1.588, 95% CI, 1.175-2.145, Conclusion: Our findings identified specific demographic and pharmacological factors associated with males and females with LOAD and EOAD. These findings suggest the need to develop strategies to eliminate disparity in the care of LOAD or EOAD patients.

Indexed as

Alzheimer’s diseaseearly onset of Alzheimer’s diseasefemalelate onset of Alzheimer’s diseasemale

Identifiers

PMID36620767
PMCPMC9815502
OpenAlexW4312187775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.