Evidence map›Paper›PMID 36620673›Full record

ArticleFrontiers in psychiatry2022

Exercise improves the social and behavioral skills of children and adolescent with autism spectrum disorders.

Chrystiane V A Toscano, José P Ferreira, Ricardo T Quinaud, Keity M N Silva, Humberto M Carvalho, Joana M Gaspar

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 7 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07068659 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Circuit Aerobic Training and Circuit Resistance Training on Cardiorespiratory Fitness, Cardiovascular Response, and Peak Expiratory Flow Rate in Autistic Spectrum Disorder Children

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled32ConditionsAutismArmsCircuit Aerobic Training, Circuit Resistance Training
NCT07104708 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Systematic Exercise Training on Core Symptoms, Executive Function and Brain Function in Children With ASD

TypeinterventionalSponsorChen LiRan2025 to 2028Enrolled70ConditionsAutism Spectrum DisorderArmsThe Child-Parent- Trainer exercise program, The regular physical training
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Food selectivity and autism: A systematic review.World journal of clinical pediatrics · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chrystiane V A ToscanoInstitute of Physical Education and Sport, Federal University of Alagoas, Maceió, Alagoas, Brazil.
José P FerreiraFaculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal.
Ricardo T QuinaudDepartment of Physical Education, School of Sports, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Keity M N SilvaPhysical Education Service, Unified Center for Integration and Development of Autism, Maceió, Alagoas, Brazil.
Humberto M CarvalhoDepartment of Physical Education, School of Sports, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Joana M GasparGraduate Program in Biochemistry, School of Biological Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Universidade Federal de Santa Catarina · BRUniversidade Federal de Alagoas · BRUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Currently, there is no standard treatment for Autism Spectrum Disorders (ASD), but there are many ways to minimize the symptoms and maximize abilities. Some studies suggest that exercise and other physical activities with children with ASD may be beneficial. In this study, we hypothesized that a physical exercise program (48-week exercise-intervention) could improve symptomatology dyad among children and adolescents with ASD. Our main aim was to examine the effects of physical activity on the primary clinical symptoms and associated comorbidities in children and adolescents with ASD. Methods: We allocated 229 children with ASD, ranging in age from 2.3-17.3 years ( Results: Our results showed that a 48-week exercise-intervention substantially decreased ASD social interaction problems, attention deficit, emotional reactivity, stereotypical verbal and motor behavior, and sleep disturbances. However, physical exercise did not affect eye contact and food selectivity. We also observed that ASD severity and socioeconomic status influence eye contact, attention deficit, and sleep disturbance responses. Conclusion: In conclusion, children and adolescents with ASD exposed to a 48-week physical exercise-intervention program had important improvements in ASD symptoms. This study highlights that structured exercise programs can be a powerful complementary therapy for the ASD population.

Indexed as

autismBayesian analysisinteractionphysical activitystereotypes

Identifiers

PMID36620673
PMCPMC9813515
OpenAlexW4312187555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.