ArticleFrontiers in psychiatry2022
Relationship between thyroid hormone and sex hormone levels and non-suicidal self-injury in male adolescents with depression.
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Could thyrotropin serum level characterize major depressive disorder phenotype? A systematic review and meta-analysis.Journal of endocrinological investigation · 2026Pooled it
- A meta-analysis on the lifetime and period prevalence of self-injury among adolescents with depression.Frontiers in public health · 2024Pooled it
- Characteristics of non-suicidal self-injury and its associations with thyroid and sex hormones in adolescents with major depressive disorder and bipolar disorder.BMC psychiatry · 2026Article
- Association of GnRH agonists with depression and suicide/self-injury: a FAERS pharmacovigilance study.Endocrine connections · 2026Article
- Psychosocial and Biological Factors Associated with Non-Suicidal Self-Injury in Chinese Child and Adolescent Inpatients with Major Depressive Disorder.Neuropsychiatric disease and treatment · 2026Article
- From anxiety and depression to non-suicidal self-injury in youths: the mediating effect of neuroticism and the moderating effect of thyroid hormones.Frontiers in psychiatry · 2026Article
- Psychological, social, and neurobiological correlates of non-suicidal self-injury and suicidal behavior in adolescents: a narrative review.Frontiers in psychiatry · 2026Review
- Interpretable prediction of one-year non-suicidal self-injury among patients with mood disorders: model development and internal evaluation.Frontiers in psychiatry · 2026Article
- Predictive value of antioxidant and thyroid function indicators for non-suicidal self-injury in adolescents with major depressive disorder.Frontiers in psychiatry · 2026Article
- A Multimodal Approach to Treatment and Management of Rumination Syndrome in a California Sea Lion (Animals : an open access journal from MDPI · 2025Article
- Associations of menstrual characteristics with non-suicidal self-injury: results from six universities in China.BMC public health · 2025Article
- High testosterone levels associated with elevated suicidal risk in male adolescents with depression.BMC psychiatry · 2025Article
- The role of testosterone and cortisol levels in nonsuicidal selfinjury in adolescents.Journal of adolescence · 2024Article
- The Thr92Ala polymorphism in the type 2 deiodinase gene is linked to depression in patients with COVID-19 after hospital discharge.Frontiers in endocrinology · 2024Article
- Development and validation of a nomogram for suicide attempts in patients with first-episode drug-naïve major depressive disorder.Frontiers in psychiatry · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Non-suicidal self-injury (NSSI) is the intentional and repeated direct injury to one's bodily tissues or organs without the intent to die, which is not socially sanctioned and does not result in death. This study will be the first to explore the relationship between NSSI behavior and thyroid hormone and sex hormone levels in male adolescents with depression. Methods: Among the inpatients in the children's ward of Shandong Mental Health Center, eighty male patients with first-episode depressive disorder were randomly selected. Forty male adolescent depressed patients with NSSI behaviors were set as the NSSI group, and forty male adolescent depressed patients without NSSI behaviors were set as the No-NSSI group. Their thyroid hormones (free triiodothyronine, free thyroxine, and thyroid stimulating hormone) and sex hormones (estradiol, progesterone, and testosterone) were measured, and the severity of self-injury in the NSSI group was assessed using the Adolescent Self-Injury Questionnaire. The NSSI group was tested again after 6 weeks of sertraline treatment for biological indicators and assessed by the Self-Injury Questionnaire to compare the hormonal differences between the NSSI group and the No-NSSI group and compare the differences of each index before and after treatment in the NSSI group. Results: T3/T4 ( Conclusion: Changes in thyroid hormone and sex hormone levels may be associated with non-suicidal self-injurious behavior in male adolescent depressed patients.
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