Evidence map›Paper›PMID 36620417›Full record

ArticleEcology and evolution2023

Phage-resistant mutations impact bacteria susceptibility to future phage infections and antibiotic response.

Lindsey W McGee, Yazid Barhoush, Rafaella Shima, Miette Hennessy

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Article
  7. Phage P100 resistance in clinical and foodborneCurrent research in microbial sciences · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Bacteriophage treatment is effective against carbapenem-resistantAntimicrobial agents and chemotherapy · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lindsey W McGeeBiology Department Earlham College Richmond Indiana USA.ORCID https://orcid.org/0000-0003-1798-5881
Yazid BarhoushBiology Department Earlham College Richmond Indiana USA.ORCID https://orcid.org/0000-0002-2357-9153
Rafaella ShimaBiology Department Earlham College Richmond Indiana USA.
Miette HennessyBiology Department Earlham College Richmond Indiana USA.
Earlham College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage (phage) therapy in combination with antibiotic treatment serves as a potential strategy to overcome the continued rise in antibiotic resistance across bacterial pathogens. Understanding the impacts of evolutionary and ecological processes to the phage-antibiotic-resistance dynamic could advance the development of such combinatorial therapy. We tested whether the acquisition of mutations conferring phage resistance may have antagonistically pleiotropic consequences for antibiotic resistance. First, to determine the robustness of phage resistance across different phage strains, we infected resistant

Indexed as

bacteriophageEscherichia colilipopolysaccharidepleiotropytrade‐offs

Identifiers

PMID36620417
PMCPMC9817185
OpenAlexW4313649358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.