Evidence map›Paper›PMID 36620386›Full record

ArticleMolecular genetics and metabolism reports2022

Considerations for prenatal and postpartum management of a female patient with ornithine transcarbamylase deficiency.

Annette Feigenbaum, Leah Lamale-Smith, Lawrence Weinstein

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Annette FeigenbaumDepartment of Pediatrics and Biochemical Genetics, Rady Children's Hospital-San Diego, University of California San Diego, 3020 Children's Way #5031, San Diego, CA 92123, USA.
Leah Lamale-SmithDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, 9300 Campus Point Drive, #7433, San Diego, CA 92037, USA.
Lawrence WeinsteinDepartment of Anesthesiology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
University of California, San Diego · USRady Children's Hospital-San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on pregnancy management and outcomes in a 27-year-old female patient with ornithine transcarbamylase (OTC) deficiency, the most common inherited enzyme deficiency in the urea cycle. Our patient was diagnosed during childhood after hyperammonemia associated with surgery and steroid treatment and was well-controlled with nitrogen scavenger treatment, low-protein diet, and L-citrulline supplementation.

Indexed as

BCAA, branched-chain amino acidsBID, twice dailyD10, 10% dextroseEAA, essential amino acidsGPB, glycerol phenylbutyrateIV, intravenousNICU, neonatal intensive care unitOrnithine transcarbamylase deficiencyOTC, ornithine transcarbamylasePeripartum managementPICC, peripherally inserted central catheterPO, per os/orallyPregnancyTID, three times dailyUCD, urea cycle disorderUrea cycle disorderX-linked, hyperammonemia

Identifiers

PMID36620386
PMCPMC9817480
OpenAlexW4285027754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.