Evidence map›Paper›PMID 36620036›Full record

ArticleFrontiers in microbiology2022

Hydrogen sulfide-sensitive Chitosan-SS-Levofloxacin micelles with a high drug content: Facile synthesis and targeted

Chunbo Lu, Wenhui Lu, Xiantao Qin, Shuyi Liang, Congmin Niu, Jiayi Guo, Yujie Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chunbo LuKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Wenhui LuKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Xiantao QinKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Shuyi LiangKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Congmin NiuKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Jiayi GuoKey Laboratory of Biology, School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, China.
Yujie XuShaanxi Key Laboratory of Natural Products and Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, China.
Weifang Medical University · CNNorthwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delivery system of antibiotics plays an important role in increasing the drug efficacy and reducing the risks of off-target toxicities and antibiotic resistance. The pathophysiology of bacterial infections is similar to that of tumor tissues, but only a few delivery systems have been able to target and release antibiotics on demand. Herein, we designed and developed a robust Chitosan-SS-Levofloxacin (CS-SS-LF) micelles for targeted antibiotic delivery, in which disulfide bond can be reduced by hydrogen sulfide (H

Indexed as

antibiotic delivery systemschitosanhydrogen sulfidemicellestargeted delivery

Identifiers

PMID36620036
PMCPMC9813597
OpenAlexW4312186509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.