Evidence map›Paper›PMID 36620020›Full record

ReviewFrontiers in microbiology2022

Activation of mucosal immunity as a novel therapeutic strategy for combating brucellosis.

David W Pascual, Zakia I Goodwin, Ella Bhagyaraj, Carol Hoffman, Xinghong Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Biological nanoparticles from Brucella abortusJournal of nanobiotechnology · 2025
    Article
  4. A Comprehensive Review of the Bovine Immune Response to Pathogens.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David W PascualDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States.
Zakia I GoodwinDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States.
Ella BhagyarajDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States.
Carol HoffmanDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States.
Xinghong YangDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States.
University of Florida · US

Funding

Mucosal Vaccines for BrucellosisR01AI123244 · NIAID · UNIVERSITY OF FLORIDA · PI PASCUAL, DAVID W · 2016 to 2020
$2.0M
Naso-oropharyngeal Brucella Infections and Mucosal Immune ProtectionR01AI125516 · NIAID · UNIVERSITY OF FLORIDA · PI PASCUAL, DAVID W · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI123244NIAID NIH HHS R01 AI125516
6 · The paper itself

Abstract

Brucellosis is a disease of livestock that is commonly asymptomatic until an abortion occurs. Disease in humans results from contact of infected livestock or consumption of contaminated milk or meat.

Indexed as

BrucellaCD8+ T cellscell-mediated immunitymucosal immunitypathogenesisresident memory T cellsvaccination

Identifiers

PMID36620020
PMCPMC9814167
OpenAlexW4312187566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.