Evidence map›Paper›PMID 36619886›Full record

ArticleEngineering in life sciences2023

Influence of oxygen concentration on the metabolism of

Agnes Janoska, Jelle J Verheijen, Wenjung Tang, Queenie Lee, Baukje Sikkema, Walter M van Gulik

Open access · goldAbstract read
In one paragraph

Article in Engineering in life sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Influence of oxygen concentration on the metabolism ofEngineering in life sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Agnes JanoskaDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Jelle J VerheijenDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Wenjung TangDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Queenie LeeDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Baukje SikkemaDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Walter M van GulikDepartment of Biotechnology Delft University of Technology Delft The Netherlands.
Delft University of Technology · NLDSM (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In large-scale bioreactors, there is often insufficient mixing and as a consequence, cells experience uneven substrate and oxygen levels that influence product formation. In this study, the influence of dissolved oxygen (DO) gradients on the primary and secondary metabolism of a high producing industrial strain of

Indexed as

black box modelmetabolic modelingoxygen limitationpenicillin pathwayscale‐down

Identifiers

PMID36619886
PMCPMC9815084
OpenAlexW4224305936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.