Evidence map›Paper›PMID 36619882›Full record

ArticleEngineering in life sciences2023

Synthetic mutualism in engineered

Tobias Müller, Simon Schick, Jonathan Beck, Georg Sprenger, Ralf Takors

Open access · goldAbstract read
In one paragraph

Article in Engineering in life sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Cooperative traits maintain bacterial niche breadth.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Stability of a MutualisticEngineering in life sciences · 2024
    Article
  3. Overexpression of RuBisCO form I and II genes inApplied and environmental microbiology · 2024
    Article
  4. Article
  5. Synthetic mutualism in engineeredEngineering in life sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tobias MüllerInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.
Simon SchickInstitute of Microbiology University of Stuttgart Stuttgart Germany.
Jonathan BeckInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.
Georg SprengerInstitute of Microbiology University of Stuttgart Stuttgart Germany.
Ralf TakorsInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.
University of Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In nature, microorganisms often reside in symbiotic co-existence providing nutrition, stability, and protection for each partner by applying "division of labor." This principle may also be used for the overproduction of targeted compounds in bioprocesses. It requires the engineering of a synthetic co-culture with distributed tasks for each partner. Thereby, the competition on precursors, redox cofactors, and energy-which occurs in a single host-is prevented. Current applications often focus on unidirectional interactions, that is, the product of partner A is used for the completion of biosynthesis by partner B. Here, we present a synthetically engineered

Indexed as

metabolic engineeringmutual auxotrophic dependencyspatially linked bioreactorssynthetic co‐culturetryptophan

Identifiers

PMID36619882
PMCPMC9815082
OpenAlexW4280508038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.