Evidence map›Paper›PMID 36619826›Full record

ReviewJournal of hazardous materials advances2022

COVID-19 pandemic lesson learned- critical parameters and research needs for UVC inactivation of viral aerosols.

Leili Abkar, Karl Zimmermann, Fuhar Dixit, Ataollah Kheyrandish, Madjid Mohseni

Open access · goldAbstract readReview
In one paragraph

Review in Journal of hazardous materials advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leili AbkarSustainable Water Innovation and Research Laboratory, Chemical and Biological Engineering Department, University of British Columbia, Canada.
Karl ZimmermannSustainable Water Innovation and Research Laboratory, Chemical and Biological Engineering Department, University of British Columbia, Canada.
Fuhar DixitSustainable Water Innovation and Research Laboratory, Chemical and Biological Engineering Department, University of British Columbia, Canada.
Ataollah KheyrandishSustainable Water Innovation and Research Laboratory, Chemical and Biological Engineering Department, University of British Columbia, Canada.
Madjid MohseniSustainable Water Innovation and Research Laboratory, Chemical and Biological Engineering Department, University of British Columbia, Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic highlighted public awareness of airborne disease transmission in indoor settings and emphasized the need for reliable air disinfection technologies. This increased awareness will carry in the post-pandemic era along with the ever-emerging SARS-CoV variants, necessitating effective and well-defined protocols, methods, and devices for air disinfection. Ultraviolet (UV)-based air disinfection demonstrated promising results in inactivating viral bioaerosols. However, the reported data diversity on the required UVC doses has hindered determining the best UVC practices and led to confusion among the public and regulators. This article reviews available information on critical parameters influencing the efficacy of a UVC air disinfection system and, consequently, the required dose including the system's components as well as operational and environmental factors. There is a consensus in the literature that the interrelation of humidity and air temperature has a significant impact on the UVC susceptibility, which translate to changing the UVC efficacy of commercialized devices in indoor settings under varying conditions. Sampling and aerosolization techniques reported to have major influence on the result interpretation and it is recommended to use several sampling methods simultaneously to generate comparable and conclusive data. We also considered the safety concerns and the potential safe alternative of UVC, far-UVC. Finally, the gaps in each critical parameter and the future research needs of the field are represented. This paper is the first step to consolidating literature towards developing a standard validation protocol for UVC air disinfection devices which is determined as the one of the research needs.

Indexed as

Aerosolization of pathogensAirborne transmissionAir sampling methodsCDC, centre for disease control and prevention (USA)CMD, count median diameterDNA, deoxyribonucleic acidDSB, double strand breakdsDNA, double-stranded deoxyribonucleic acidFar-UVCFar-UVC, ultraviolet irradiation in the ‘far’ range of 200–230 nmGTC, growth tube collectorsLED, light emitting diodeLPUV, low-pressure ultraviolet lampNIOSH, national institute for occupational safety and healthParticle size distributionPBS, phosphate buffered salinePRRS, porcine reproductive and respiratory syndromeREL, recommended exposure limitRH, relative humidityRNA, ribonucleic acidROS, reactive oxygen speciesSARS-CoV-2, severe acute respiratory syndrome coronavirus-2SSB, single strand breakssRNA, single-stranded ribonucleic acidSuspending mediaUVC, ultraviolet irradiation in the ‘C’, or germicidal, spectrum from 200 to 290 nmUVGI, ultraviolet germicidal irradiationUV-LED, light emitting diode in the ultraviolet rangeUV, ultraviolet irradiationViral UVC susceptibility

Identifiers

PMID36619826
PMCPMC9553962
OpenAlexW4304688100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.