Evidence map›Paper›PMID 36619803›Full record

ArticleBehavioural neurology2022

Chronic Inhibition of Aggressive Behavior Induces Behavioral Change in Mice.

Hiroshi Ueno, Yu Takahashi, Shinji Murakami, Kenta Wani, Tetsuji Miyazaki, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara

Abstract read
In one paragraph

Article in Behavioural neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroshi UenoDepartment of Medical Technology, Kawasaki University of Medical Welfare, Okayama 701-0193, Japan.ORCID https://orcid.org/0000-0003-0360-5761
Yu TakahashiDepartment of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Shinji MurakamiDepartment of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Kenta WaniDepartment of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Tetsuji MiyazakiDepartment of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Yosuke MatsumotoDepartment of Neuropsychiatry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Motoi OkamotoDepartment of Medical Technology, Graduate School of Health Sciences, Okayama University, Okayama 700-8558, Japan.
Takeshi IshiharaDepartment of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suppression of anger is more common than its expression among Asian individuals. Emotional suppression is considered an unhealthy emotional regulation. Most studies on emotional suppression have concluded that suppression adversely affects social outcomes, with approximately 5% of the world's population suffering from emotional disorders. However, anger suppression has not received academic attention, and details of the effects of chronic anger suppression on the central nervous system remain unclear. In this study, we performed the resident-intruder test to investigate the effect of chronic suppression of aggressive behavior in mice using a behavioral test battery and to clarify whether suppression of this aggressive behavior is stressful for mice. Mice chronically inhibited aggressive behavior and lost weight. Mice with inhibited aggressive behavior showed a reduced percentage of immobility time during the tail suspension test as well as no changes in activity, anxiety-like behavior, muscle strength, or temperature sensitivity. This study provides scientific evidence for the effects of chronic aggressive behavior inhibition on the body and central nervous system.

Indexed as

AggressionAnxietyAnimalsBehavior, AnimalMice

Identifiers

PMID36619803
PMCPMC9815925

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.