Evidence map›Paper›PMID 36619740›Full record

ArticleFrontiers in cellular and infection microbiology2022

Phenotype and function of peripheral blood γδ T cells in HIV infection with tuberculosis.

Shi Zou, Yanni Xiang, Wei Guo, Qi Zhu, Songjie Wu, Yuting Tan, Yajun Yan, Ling Shen, Yong Feng, Ke Liang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Enrichment of CD4iScience · 2026
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  5. Enrichment of a CD4bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Shi ZouDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yanni XiangDepartment of Intensive Care Medicine, Yichang Central People's Hospital, Yichang, China.
Wei GuoWuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
Qi ZhuWuhan Pulmonary Hospital, Wuhan Institute for Tuberculosis Control, Wuhan, China.
Songjie WuWuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
Yuting TanDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yajun YanDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ling ShenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, United States.
Yong FengDepartment of Medical Microbiology, Wuhan University School of Basic Medical Sciences, Wuhan, China.
Ke LiangDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNZhongnan Hospital of Wuhan University · CNUniversity of Illinois Chicago · USWuhan Center for Disease Control and Prevention · CNWuhan Pulmonary Hospital · CNYichang Central People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although γδ T cells play an essential role in immunity against Methods: The phenotypic and functional properties of peripheral blood γδ T cells in patients with HIV/TB co-infection were analyzed compared to healthy controls and patients with HIV mono-infection or TB by direct intracellular cytokine staining (ICS). Results: The percentage of Vδ Conclusions: Our data suggested that HIV/TB co-infection altered the balance of γδ T cell subsets. The influence of HIV/TB co-infection on the function of γδ T cells to produce cytokines was complicated, which will shed light on further investigations on the mechanisms of the immune response against HIV and/or MTB infection.

Indexed as

CoinfectionHIV InfectionsMycobacterium tuberculosisTuberculosisCytokinesHumansPhenotypeReceptors, Antigen, T-Cell, gamma-deltaT-Lymphocyte SubsetsCytokinesReceptors, Antigen, T-Cell, gamma-deltaHIVIL-17ATNF-αtuberculosis (TB)γδ T cells

Identifiers

PMID36619740
PMCPMC9816428
OpenAlexW4312176355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.