Evidence map›Paper›PMID 36619632›Full record

ArticleFrontiers in medicine2022

Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells.

Kazuma Kobayashi, Toshikazu Ozeki, Hangsoo Kim, Masaki Imai, Hiroshi Kojima, Daiki Iguchi, Sosuke Fukui, Masafumi Suzuki, Yasuhiro Suzuki, Shoichi Maruyama and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Kazuma KobayashiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Toshikazu OzekiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hangsoo KimDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masaki ImaiDepartment of Immunology, Nagoya City University Graduate School of Medicine, Nagoya, Japan.
Hiroshi KojimaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Daiki IguchiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sosuke FukuiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masafumi SuzukiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yasuhiro SuzukiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shoichi MaruyamaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yasuhiko ItoDepartment of Nephrology and Rheumatology, Aichi Medical University, Nagakute, Japan.
Masashi MizunoDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPAichi Medical University · JPNagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The membrane complement regulators (CRegs) CD46, CD55, and CD59 are highly expressed on human peritoneal mesothelial cells. However, how mesothelial CRegs change according to the peritoneal dialysis (PD) history of patients has remained unclear. We therefore examined longitudinal changes in CRegs in primary cultured mesothelial cells from PD patients (human peritoneal mesothelial cells; HPMCs) and examined which components of PD fluid (PDF) affect CRegs

Indexed as

complementcomplement regulatormesothelial cellsperitoneal dialysateperitoneal dialysis

Identifiers

PMID36619632
PMCPMC9815709
OpenAlexW4311949730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.