Evidence map›Paper›PMID 36619471›Full record

ArticleHeliyon2022

Validation of skeletal muscle and adipose tissue measurements using a fully automated body composition analysis neural network versus a semi-automatic reference program with human correction in patients with lung cancer.

Cecily A Byrne, Yanyu Zhang, Giamila Fantuzzi, Thomas Geesey, Palmi Shah, Sandra L Gomez

Abstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cecily A ByrneUniversity of Illinois at Chicago, College of Applied Health Sciences, Department of Kinesiology and Nutrition, 1919 W. Taylor Street Chicago IL 60612, USA.
Yanyu ZhangRush University Medical Center, Rush Bioinformatics and Biostatistics Core, 1653 West Congress Parkway Chicago IL 60612, USA.
Giamila FantuzziUniversity of Illinois at Chicago, College of Applied Health Sciences, Department of Kinesiology and Nutrition, 1919 W. Taylor Street Chicago IL 60612, USA.
Thomas GeeseyRush University Medical Center, Department of Radiology, 1653 West Congress Parkway, Chicago, IL 60612, USA.
Palmi ShahRush University Medical Center, Department of Radiology, 1653 West Congress Parkway, Chicago, IL 60612, USA.
Sandra L GomezRush University, Department of Clinical Nutrition, 600 S Paulina St, AAC 737D, Chicago, IL 60612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale and objectives: To validate skeletal muscle and adipose tissues cross sectional area (CSA) and densities between a fully automated neural network (test program) and a semi-automated program requiring human correction (reference program) for lumbar 1 (L1) and lumbar 2 (L2) CT scans in patients with lung cancer. Materials and methods: Agreement between the reference and test programs was measured using Dice-similarity coefficient (DSC) and Bland-Altman plots with limits of agreement within 1.96 standard deviation. Results: A total of 49 L1 and 47 L2 images were analyzed from patients with lung cancer (mean age = 70.51 ± 9.48 years; mean BMI = 27.45 ± 6.06 kg/m Conclusion: The use of a fully automated neural network to analyze body composition at L1 and L2 in patients with lung cancer is valid for measuring skeletal muscle and adipose tissue CSA and densities when compared to a reference program. Further validation in a more diverse sample and in different disease and health states is warranted to increase the generalizability of the test program at L1 and L2.

Indexed as

Adipose tissueAutomated segmentationBody compositionComputed tomographyLumbar 1 and 2Skeletal muscleValidation

Identifiers

PMID36619471
PMCPMC9816970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.