Evidence map›Paper›PMID 36619377›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme.

Marco Pitino, Laura A Fleites, Lauren Shrum, Michelle Heck, Robert G Shatters

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marco PitinoAgroSource, Inc, Jupiter, FL, United States.
Laura A FleitesAgroSource, Inc, Jupiter, FL, United States.
Lauren ShrumAgroSource, Inc, Jupiter, FL, United States.
Michelle HeckEmerging Pests and Pathogens Research Unit, USDA Agricultural Research Service, Ithaca, NY, United States.
Robert G ShattersU.S. Horticultural Research Laboratory, Subtropical Insects and Horticulture Research Unit, USDA Agricultural Research Service, Fort Pierce, FL, United States.
Agricultural Research Service · USU.S. Horticultural Research Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanobodies

Indexed as

ACE2biofactorycompetitive ELISAnanobodyplantplant cell cultureSARS-CoV-2VHH

Identifiers

PMID36619377
PMCPMC9822723
OpenAlexW4312116172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.