Evidence map›Paper›PMID 36619235›Full record

ArticleJournal of obesity2022

A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population.

Sudharmadevi K Manju, Thottathil R Anilkumar, G Vysakh, Balakumaran K Leena, Vijayalekshmi Lekshminarayan, Pradeep G Kumar, Trivikrama K Shenoy

Open access · goldAbstract read
In one paragraph

Article in Journal of obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Association betweenBiomolecules & therapeutics · 2024
    Article
  2. Review
  3. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sudharmadevi K ManjuDepartment of Biochemistry, Sree Gokulam Medical College and Research Foundation, Thiruvananthapuram 695607, Kerala, India.ORCID 0000-0001-7979-1076
Thottathil R AnilkumarDivision of Molecular Reproduction, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram 695014, Kerala, India.ORCID 0000-0001-7982-9265
G VysakhDivision of Molecular Reproduction, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram 695014, Kerala, India.ORCID 0000-0002-4882-9614
Balakumaran K LeenaPopulation Health and Research Institute, Medical College P.O., Thiruvananthapuram 695011, Kerala, India.ORCID 0000-0002-8885-4398
Vijayalekshmi LekshminarayanDepartment of Applied Nutrition (Retd), Government Medical College, Thiruvananthapuram 695011, Kerala, India.
Pradeep G KumarDivision of Molecular Reproduction, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram 695014, Kerala, India.ORCID 0000-0001-7603-3579
Trivikrama K ShenoyDepartment of Gastroenterology, Sree Gokulam Medical College and Research Foundation, Thiruvananthapuram 695607, Kerala, India.ORCID 0000-0002-2826-6869
Rajiv Gandhi Centre for Biotechnology · INSree Gokulam Medical College and Research Foundation · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Over the last few years, the importance of leptin in energy metabolism has been extensively studied in both animal models and in humans. Very few results are available on the association between human leptin gene ( Methods: In this case-control design of 148 study participants, data were collected on socioeconomic aspects and anthropometric measurements. Plasma glucose, insulin, leptin, and lipid profile were measured. Genotyping was done by automated DNA sequencing. Results: The common Single Nucleotide Polymorphism (SNP) of 5'-UTR of Conclusion:

Indexed as

LeptinObesity, MorbidCase-Control StudiesHumansIndiaObesityPolymorphism, Single NucleotideReceptors, LeptinLEP protein, humanLeptinReceptors, Leptin

Identifiers

PMID36619235
PMCPMC9812639
OpenAlexW4313331930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.