Evidence map›Paper›PMID 36619221›Full record

ArticleInternational journal of medical sciences2023

EZH2 promotes angiogenesis in peritoneal dialysis by epigenetically activating SP4 expression in the IL-6/sIL-6R signalling pathway.

Nan Zhu, Haochen Guan, Xuan Wang, Yueyue Zhang, Lijie Gu, Jieshuang Jia, Ling Wang, Weijie Yuan

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. DifferentialScience advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nan ZhuDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Haochen GuanDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Xuan WangDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Yueyue ZhangDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Lijie GuDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Jieshuang JiaDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Ling WangDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
Weijie YuanDepartment of Nephrology, Shanghai General Hospital, Shanghai, China.
SAIC-GM (China) · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enhancer of Zeste Homolog 2 ProteinInterleukin-6Peritoneal DialysisReceptors, Interleukin-6Sp4 Transcription FactorAnimalsEpigenesis, GeneticHumansHuman Umbilical Vein Endothelial CellsRatsSignal TransductionVascular Endothelial Growth Factor AEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanEZH2 protein, ratIL6R protein, humanIl6r protein, ratInterleukin-6Receptors, Interleukin-6SP4 protein, humanSp4 protein, ratSp4 Transcription FactorVascular Endothelial Growth Factor AangiogenesisEZH2IL-6/sIL-6Rperitoneal dialysisSP4VEGF

Identifiers

PMID36619221
PMCPMC9812808
OpenAlexW4313579908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.