Evidence map›Paper›PMID 36618705›Full record

ReviewFrontiers in nutrition2022

Recent advances of γ-aminobutyric acid: Physiological and immunity function, enrichment, and metabolic pathway.

Zhou Heli, Chen Hongyu, Bao Dapeng, Tan Yee Shin, Zhong Yejun, Zhang Xi, Wu Yingying

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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  20. Whole-Genome Sequence Analysis ofJournal of fungi (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhou HeliSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Chen HongyuNational Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization of Ministry of Agriculture, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai, China.
Bao DapengSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Tan Yee ShinFaculty of Science and Mushroom Research Centre, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia.
Zhong YejunState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi, China.
Zhang XiBannerBio Nutraceuticals Inc., Shenzhen, China.
Wu YingyingNational Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization of Ministry of Agriculture, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

γ-aminobutyric acid (GABA) is a non-protein amino acid which naturally and widely occurs in animals, plants, and microorganisms. As the chief inhibitory neurotransmitter in the central nervous system of mammals, it has become a popular dietary supplement and has promising application in food industry. The current article reviews the most recent literature regarding the physiological functions, preparation methods, enrichment methods, metabolic pathways, and applications of GABA. This review sheds light on developing GABA-enriched plant varieties and food products, and provides insights for efficient production of GABA through synthetic biology approaches.

Indexed as

anabolismbiofortification breedingcatabolismenvironmental stressGABAmicrobial fermentationneurotransmitter

Identifiers

PMID36618705
PMCPMC9813243

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.