Evidence map›Paper›PMID 36618683›Full record

ArticleFrontiers in nutrition2022

A new iron supplement: The chelate of pig skin collagen peptide and Fe

Shan Jiang, Weichao Dong, Zhen Zhang, Jing Xu, Haoran Li, Jiayu Zhang, Long Dai, Shaoping Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shan JiangSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Weichao DongSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Zhen ZhangSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Jing XuSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Haoran LiSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Jiayu ZhangSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Long DaiSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Shaoping WangSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Binzhou Medical University · CNBinzhou University · CNShandong University of Traditional Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Iron deficiency anemia (IDA) is one of the most common nutritional diseases encountered all over the world. Nowadays, oral iron supplementation is still the mainstay of IDA treatment. Methods: In this study, a new iron nutritional supplement named pig skin collagen peptides ferrous chelates (PSCP-Fe) was prepared, and its structure was characterized by the scanning electron microscopy, sykam amino acid analyzer and Fourier transform infrared spectroscopy (FTIR). The anti-IDA activity of PSCP-Fe was evaluated in low-Fe Results: The results of amino acid analysis and FTIR showed that aspartic acid (Asp), arginine (Arg), histidine (His), glutamic acid (Glu), cystine (Cys), and lysine (Lys) residued in PSCP chelated readily with Fe Discussion: Overall, our results elucidate the interactions between gut bacteria and related cytokines and reveal the mechanisms underlying the anti-IDA effect of PSCP-Fe. They will thus provide a theoretical foundation for PSCP-Fe as a new iron nutritional supplement.

Indexed as

gut florairon deficiency anemiairon nutritional supplementpeptides-ferrous chelatestructural characterization

Identifiers

PMID36618683
PMCPMC9815456
OpenAlexW4312187932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.