Evidence map›Paper›PMID 36618468›Full record

ArticleJournal of education and health promotion2022

Comparison of the effect of ferrous sulfate and ferrous gluconate on prophylaxis of iron deficiency in toddlers 6-24 months old: A randomized clinical trial.

Vahid Falahati, Ali Ghasemi, Kazem Ghaffari, Aziz Eghbali, Sanaz Khodabakhshi, Amir Almasi-Hashiani, Bahman Sadeghi-Sedeh, Mostafa Shanbehzadeh

Open access · goldAbstract read
In one paragraph

Article in Journal of education and health promotion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Iron dysregulation in the central nervous system: implications for autism spectrum disorder.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Vahid FalahatiClinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran.
Ali GhasemiDepartment of Biochemistry and Hematology, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Kazem GhaffariDepartment of Basic and Laboratory Sciences, Khomein University of Medical Sciences, Khomein, Iran.
Aziz EghbaliClinical Research Development Center of Aliasghar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Sanaz KhodabakhshiClinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran.
Amir Almasi-HashianiDepartment of Epidemiology, Arak University of Medical Sciences, Arak, Iran.
Bahman Sadeghi-SedehDepartment of Social Medicine, Arak University of Medical Sciences, Arak, Iran.
Mostafa ShanbehzadehDepartment of Health Information Technology, Faculty of Paramedical, Ilam University of Medical Sciences, Ilam, Iran.
Arak University of Medical Sciences · IRImam Khomeini Hospital · IRIran University of Medical Sciences · IRMedical University of Ilam · IRSemnan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIron deficiency anemia (IDA) is one of the most common anemias, especially in children 4-23 months. Therefore, prophylaxis is necessary to improve iron status as well as reduce IDA in Toddlers. The aim of this study was to compare the efficacy of daily supplementation with ferrous gluconate (FG) and ferrous sulfate (FS) on iron status in toddlers. MATERIALS AND

methodsA total of 120 healthy toddlers were divided randomly into 2 groups at the Amir-Kabir Hospital, Arak, Iran and received FS and FG from March 2020 to December 2020. Iron status was evaluated at baseline and after 6 months of supplementation. The statistical significance of the differences in iron status between FS and FG groups was calculated using Student's

resultsComparison of iron status of FS and FG groups toddlers at baseline and after 6 months of supplementation showed that there was a significant difference in hemoglobin (Hb) (10.46 vs. 12.45,

conclusionsAlthough prophylaxis with FG led to a higher Hb and ferritin levels, our study recommended that both FG and FS supplements were effective for prophylactic use in the prevention of IDA. However, FG was more effective than FS because FG group that received FG supplementation indicated a higher Hb and ferritin levels in comparison to the FS group that received FS supplementation.

Indexed as

Anemiaferrous gluconateferrous sulfateironiron deficienciesprophylaxis

Identifiers

PMID36618468
PMCPMC9818626
OpenAlexW4312505847

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.