Evidence map›Paper›PMID 36618379›Full record

ReviewFrontiers in immunology2022

CARMA3: A potential therapeutic target in non-cancer diseases.

Zhen Gui, Yan Zhang, Aihua Zhang, Weiwei Xia, Zhanjun Jia

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Astragalus polysaccharide mitigates the airway inflammation in bronchial asthma by regulating Hedgehog/NLRP3/GSDMD pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhen GuiDepartment of Clinical Laboratory, Children's Hospital of Nanjing Medical University, Nanjing, China.
Yan ZhangDepartment of Clinical Laboratory, Children's Hospital of Nanjing Medical University, Nanjing, China.
Aihua ZhangDepartment of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Weiwei XiaDepartment of Clinical Laboratory, Children's Hospital of Nanjing Medical University, Nanjing, China.
Zhanjun JiaDepartment of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Second Affiliated Hospital of Nanjing Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caspase recruitment domain and membrane-associated guanylate kinase-like protein 3 (CARMA3) is a scaffold protein widely expressed in non-hematopoietic cells. It is encoded by the caspase recruitment domain protein 10 (

Indexed as

Adaptor Proteins, Signal TransducingCARD Signaling Adaptor ProteinsNeoplasmsB-Cell CLL-Lymphoma 10 ProteinCaspasesHumansNeoplasm ProteinsReceptor Protein-Tyrosine KinasesReceptors, G-Protein-CoupledAdaptor Proteins, Signal TransducingB-Cell CLL-Lymphoma 10 ProteinCARD10 protein, humanCARD Signaling Adaptor ProteinsCaspasesNeoplasm ProteinsReceptor Protein-Tyrosine KinasesReceptors, G-Protein-CoupledBCL10CARMA3MALT1NF-κBnon-cancer diseases

Identifiers

PMID36618379
PMCPMC9815110
OpenAlexW4312098512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.