Evidence map›Paper›PMID 36618277›Full record

ArticleArchives of Razi Institute2022

Effect of Daily Rhythms of Cortisol Secretion on the Rate of Aging in Men.

S G Gorelik, O N Belousova, E V Treneva, S V Bulgakova, N O Zakharova, S A Nesterenko

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of Razi Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

S G GorelikBelgorod State University, Pobedy Str., 85, Belgorod, Russia, 308015.
O N BelousovaBelgorod State University, Pobedy Str., 85, Belgorod, Russia, 308015.
E V TrenevaSamara State Medical University, Chapaevskaya Str., 89, Samara, Russia, 443009.
S V BulgakovaSamara State Medical University, Chapaevskaya Str., 89, Samara, Russia, 443009.
N O ZakharovaSamara State Medical University, Chapaevskaya Str., 89, Samara, Russia, 443009.
S A NesterenkoSamara State Medical University, Chapaevskaya Str., 89, Samara, Russia, 443009.
Samara State Medical University · RUBelgorod National Research University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenomenon of human aging is the result of a complex interaction among several factors in which the immune system plays a key role. Cortisol is a glucocorticoid secreted by the adrenal gland and has a specific secretion pattern. The current study aimed at identifying the cause and pathogenesis of premature aging using biological markers. This study was performed based on the results of clinical and instrumental examinations on 91 middle-aged men aged 45-59 years. VaseraVS-1500 sphygmomanometer based on standard methods was used to measure biological age. The relationship between biological age and circadian rhythms of cortisol secretion was calculated to elucidate the pathophysiological mechanisms of aging development. The recorded data showed that the violation of the circadian rhythms of cortisol secretion characterized by a consistently high level of the hormone throughout the day was typical among individuals with accelerated types of aging. Based on the obtained data, a formula for determining the biological age of the studied groups of patients was prepared by considering the circadian rhythm of cortisol secretion, which can be an additional tool for early detection of aging in men.

Indexed as

AgingHydrocortisoneCircadian RhythmHumansMaleMiddle AgedHydrocortisoneAging markersBiological ageCortisolPremature aging

Identifiers

PMID36618277
PMCPMC9759242
OpenAlexW4315435872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.