Evidence map›Paper›PMID 36618245›Full record

ArticleJournal of family medicine and primary care2022

Prognostication of COVID-19 patients using ROX index and CURB-65 score - A retrospective observational study.

Poonam Arora, Takshak Shankar, Shrirang Joshi, Aadya Pillai, Ankita Kabi, Rajnish K Arora, Meenakshi Khapre, Nilotpal Chowdhury

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Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Poonam AroraDepartment of Emergency Medicine, AIIMS Rishikesh, Uttarakhand, India.
Takshak ShankarDepartment of Emergency Medicine, AIIMS Rishikesh, Uttarakhand, India.
Shrirang JoshiDepartment of Emergency Medicine, AIIMS Rishikesh, Uttarakhand, India.
Aadya PillaiDepartment of Emergency Medicine, AIIMS Rishikesh, Uttarakhand, India.
Ankita KabiDepartment of Emergency Medicine, AIIMS Rishikesh, Uttarakhand, India.
Rajnish K AroraDepartment of Neurosurgery, AIIMS Rishikesh, Uttarakhand, India.
Meenakshi KhapreDepartment of Community and Family Medicine, AIIMS Rishikesh, Uttarakhand, India.
Nilotpal ChowdhuryDepartment of Pathology, AIIMS Rishikesh, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Coronavirus disease-2019 (COVID-19) disease has overwhelmed the healthcare infrastructure worldwide. The shortage of intensive care unit (ICU) beds leads to longer waiting times and higher mortality for patients. High crowding leads to an increase in mortality, length of hospital stays, and hospital costs for patients. Through an appropriate stratification of patients, rational allocation of the available hospital resources can be accomplished. Various scores for risk stratification of patients have been tried, but for a score to be useful at primary care level, it should be readily available at the bedside and be reproducible. ROX index and CURB-65 are simple bedside scores, requiring minimum equipment, and investigations to calculate. Methods: This retrospective, record-based study included adult patients who presented to the ED from May 1, 2020 to November 30, 2020 with confirmed COVID-19 infection. The patient's clinical and demographic details were obtained from the electronic medical records of the hospital. ROX index and CURB-65 score on ED arrival were calculated and correlated with the need for hospitalization and early (14-day) and late (28-day) mortality. Results: 842 patients were included in the study. The proportion of patients with mild, moderate and severe disease was 46.3%, 14.9%, and 38.8%, respectively. 55% patients required hospitalization. The 14-day mortality was 8.8% and the 28-day mortality was 20.7%. The AUROC of ROX index for predicting hospitalization was 0.924 (p < 0.001), for 14-day mortality was 0.909 (p < 0.001) and for 28-day mortality was 0.933 (p < 0.001). The AUROC of CURB-65 score for predicting hospitalization was 0.845 (p < 0.001), for 14-day mortality was 0.905 (p < 0.001) and for 28-day mortality was 0.902 (p < 0.001). The cut-off of ROX index for predicting hospitalization was ≤18.634 and for 14-day mortality was ≤14.122. Similar cut-off values for the CURB-65 score were ≥1 and ≥2, respectively. Conclusion: ROX index and CURB-65 scores are simple and inexpensive scores that can be efficiently utilised by primary care physicians for appropriate risk stratification of patients with COVID-19 infection.

Indexed as

COVID-19CURB-65 scoreprognostic scorerisk-stratificationROX index

Identifiers

PMID36618245
PMCPMC9810859

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