ArticleJournal of family medicine and primary care2022
To study thyroid hormone levels (FT3, FT4, and TSH levels) in critically ill children and their correlation with disease severity and clinical outcome in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand.
Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- The Impact of Non-Thyroidal Illness Syndromes on The Prognosis and Immune Profile in Severe Fever with Thrombocytopenia Syndrome Patients.Infection and drug resistance · 2025Article
- The Role of Toll-like Receptor 2 (TLR2) in the Development and Progression of Hashimoto's Disease (HD): A Case Study on Female Patients in Poland.International journal of molecular sciences · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
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Abstract
Introduction: There are manifold effects on neuro-endocrine and metabolic systems due to critical illness. Abnormalities in thyroid hormone levels in a critically-ill patient with no pre-existing hypothalamo-pituitary-thyroid dysfunction is seen in Euthyroid sick syndrome or Non thyroidal illness syndrome. The understanding of different endocrinal changes in acute phase of critical illness may help us to intervene early and improve by pharmacological intervention. Materials and Methods: Critically ill children admitted in PICU, RIMS, Ranchi, aged 29 days to 17 years. Results: In our study, it was seen that FT3 and FT4 were low at admission at admission in critically ill children. And among them, the non-survivors had significantly lower values compared to survivors. Discussion: Among this critically ill patient, more than 70% of patients have shown low free T3 (Type I NTIS) and around 50% of low free T4 levels and free T3 levels (Type II NTIS). We have done this study to assess the thyroid dysfunction in critically ill children admitted in our PICU and its correlation with disease severity and clinical outcome.
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