Evidence map›Paper›PMID 36617673›Full record

ArticleRNA (New York, N.Y.)2023

RNA:RNA interaction in ternary complexes resolved by chemical probing.

Elnaz Banijamali, Lorenzo Baronti, Walter Becker, Joanna J Sajkowska-Kozielewicz, Ting Huang, Christina Palka, David Kosek, Lara Sweetapple, Juliane Müller, Michael D Stone and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Elnaz BanijamaliDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0003-4718-9720
Lorenzo BarontiDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0001-5393-3822
Walter BeckerDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.
Joanna J Sajkowska-KozielewiczDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.
Ting HuangDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.
Christina PalkaDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.
David KosekDepartment of Cell and Molecular Biology, Karolinska Institute, 17177 Stockholm, Sweden.
Lara SweetappleDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.
Juliane MüllerDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.
Michael D StoneDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.
Emma R AnderssonDepartment of Cell and Molecular Biology, Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0002-8608-625X
Katja PetzoldDepartment of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden katja.petzold@ki.se.ORCID 0000-0001-9470-0347
Karolinska Institutet · SEUniversity of California, Santa Cruz · USStellenbosch University · ZA

Funding

Structure and dynamics of the Tetrahymena telomerase ribonucleoproteinR01GM095850 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI STONE, MICHAEL D · 2011 to 2023
$4.4M
NIGMS NIH HHS R01 GM095850
6 · The paper itself

Abstract

RNA regulation can be performed by a second targeting RNA molecule, such as in the microRNA regulation mechanism. Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE) probes the structure of RNA molecules and can resolve RNA:protein interactions, but RNA:RNA interactions have not yet been addressed with this technique. Here, we apply SHAPE to investigate RNA-mediated binding processes in RNA:RNA and RNA:RNA-RBP complexes. We use

Indexed as

MicroRNAsArgonaute ProteinsRNA-Induced Silencing ComplexRNA InterferenceRNA, MessengerArgonaute ProteinsMicroRNAsRNA-Induced Silencing ComplexRNA, MessengerMiR targeting/RISCRNA biophysicsRNA:RNA bindingRNA secondary structureSHAPE

Identifiers

PMID36617673
PMCPMC9945442
OpenAlexW4313448527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.