Evidence map›Paper›PMID 36617663›Full record

ArticleGenome research2023

Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera.

Peter O Mulhair, Liam Crowley, Douglas H Boyes, Amber Harper, Owen T Lewis, Darwin Tree of Life Consortium, Peter W H Holland

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  4. Why sequence the genome of every species? A view from evolutionary biology.Journal of the Marine Biological Association of the United Kingdom. Marine Biological Association of the United Kingdom · 2025
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  8. eLife · 2024
    Article
  9. Ensembl 2024.Nucleic acids research · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peter O MulhairDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Liam CrowleyDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Douglas H BoyesDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Amber HarperDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Owen T LewisDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Darwin Tree of Life Consortium
Peter W H HollandDepartment of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.ORCID 0000-0003-1533-9376
University of Oxford · GB

Funding

Wellcome TrustWellcome Trust 218328
6 · The paper itself

Abstract

Homeobox genes encode transcription factors with essential roles in patterning and cell fate in developing animal embryos. Many homeobox genes, including Hox and NK genes, are arranged in gene clusters, a feature likely related to transcriptional control. Sparse taxon sampling and fragmentary genome assemblies mean that little is known about the dynamics of homeobox gene evolution across Lepidoptera or about how changes in homeobox gene number and organization relate to diversity in this large order of insects. Here we analyze an extensive data set of high-quality genomes to characterize the number and organization of all homeobox genes in 123 species of Lepidoptera from 23 taxonomic families. We find most Lepidoptera have around 100 homeobox loci, including an unusual Hox gene cluster in which the

Indexed as

ButterfliesGenes, HomeoboxAnimalsEvolution, MolecularGenomicsMultigene FamilyPhylogeny

Identifiers

PMID36617663
PMCPMC9977156
OpenAlexW4311887599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.