ArticleEuropean journal of applied physiology2023
Defining left ventricular remodeling using lean body mass allometry: a UK Biobank study.
Article in European journal of applied physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Deep Learning-Based Algorithm for the Classification of Left Ventricle Segments by Hypertrophy Severity.Journal of imaging · 2025Article
- Exercise echocardiography for improved assessment of diastolic filling dynamics.Experimental physiology · 2025Article
- Tipping the scale: Effects of physical activity and body composition on cardiac parameters in postmenopausal females.Physiological reports · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
purposeThe geometric patterns of ventricular remodeling are determined using indexed left ventricular mass (LVM), end-diastolic volume (LVEDV) and concentricity, most often measured using the mass-to-volume ratio (MVR). The aims of this study were to validate lean body mass (LBM)-based allometric coefficients for scaling and to determine an index of concentricity that is independent of both volume and LBM.
methodsParticipants from the UK Biobank who underwent both CMR and dual-energy X-ray absorptiometry (DXA) during 2014-2015 were considered (n = 5064). We excluded participants aged ≥ 70 years or those with cardiometabolic risk factors. We determined allometric coefficients for scaling using linear regression of the logarithmically transformed ventricular remodeling parameters. We further defined a multiplicative allometric relationship for LV concentricity (LVC) adjusting for both LVEDV and LBM.
resultsA total of 1638 individuals (1057 female) were included. In subjects with lower body fat percentage (< 25% in males, < 35% in females, n = 644), the LBM allometric coefficients for scaling LVM and LVEDV were 0.85 ± 0.06 and 0.85 ± 0.03 respectively (R
conclusionsWe validated allometric coefficients for LBM-based scaling for CMR indexed parameters relevant for classifying geometric patterns of ventricular remodeling.
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